Literature DB >> 17826090

On-resin cyclization of peptide ligands of the Vascular Endothelial Growth Factor Receptor 1 by copper(I)-catalyzed 1,3-dipolar azide-alkyne cycloaddition.

Victor Goncalves1, Benoit Gautier, Anne Regazzetti, Pascale Coric, Serge Bouaziz, Christiane Garbay, Michel Vidal, Nicolas Inguimbert.   

Abstract

Cyclic peptides were obtained, on-resin, by the copper (I) catalysed 1,3-dipolar cycloaddition of azides and alkynes. The reaction led exclusively to the formation of the expected cyclomonomeric products which acted as ligands of the Vascular Endothelial Growth Factor receptor 1.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 17826090     DOI: 10.1016/j.bmcl.2007.07.087

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  6 in total

1.  Synthesis of novel cyclic NGR/RGD peptide analogs via on resin click chemistry.

Authors:  Belhu B Metaferia; Matthew Rittler; Jinesh S Gheeya; Albert Lee; Heidi Hempel; Alberto Plaza; William G Stetler-Stevenson; Carole A Bewley; Javed Khan
Journal:  Bioorg Med Chem Lett       Date:  2010-10-21       Impact factor: 2.823

2.  Peptide tertiary structure nucleation by side-chain crosslinking with metal complexation and double "click" cycloaddition.

Authors:  Oscar Torres; Deniz Yüksel; Matt Bernardina; Krishna Kumar; Dennis Bong
Journal:  Chembiochem       Date:  2008-07-21       Impact factor: 3.164

3.  Peptide cyclization and cyclodimerization by Cu(I)-mediated azide-alkyne cycloaddition.

Authors:  Reshma Jagasia; Justin M Holub; Markus Bollinger; Kent Kirshenbaum; M G Finn
Journal:  J Org Chem       Date:  2009-04-17       Impact factor: 4.354

4.  Inhibiting EGFR dimerization using triazolyl-bridged dimerization arm mimics.

Authors:  Laura E Hanold; Krishnadev Oruganty; Norman T Ton; Aaron M Beedle; Natarajan Kannan; Eileen J Kennedy
Journal:  PLoS One       Date:  2015-03-19       Impact factor: 3.240

Review 5.  Synthesis of novel cyclopeptides containing heterocyclic skeletons.

Authors:  Fatima Hamdan; Fatemeh Tahoori; Saeed Balalaie
Journal:  RSC Adv       Date:  2018-10-03       Impact factor: 4.036

6.  Detection of highly curved membrane surfaces using a cyclic peptide derived from synaptotagmin-I.

Authors:  Jonel P Saludes; Leslie A Morton; Nilanjan Ghosh; Lida A Beninson; Edwin R Chapman; Monika Fleshner; Hang Yin
Journal:  ACS Chem Biol       Date:  2012-07-17       Impact factor: 5.100

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.