Literature DB >> 17826076

The 4-portal technique decreases adverse effects in preoperative radiotherapy for advanced rectal cancer: comparison between the 2-portal and the 4-portal techniques.

Tomomichi Kiyomatsu1, Toshiaki Watanabe, Tetsuichiro Muto, Hirokazu Nagawa.   

Abstract

BACKGROUND: This study evaluated the difference of postoperative complications according to the radiation technique after preoperative radiotherapy for rectal cancer.
METHODS: Among 224 patients with rectal cancer who underwent preoperative radiotherapy, 159 patients were treated with the 2-portal technique and 65 patients with the 4-portal technique. Comparison was performed between these 2 groups.
RESULTS: The 5-year disease-free survival and local recurrence rate showed no difference between the 2 groups. There was also no difference in postoperative mortality. However, the 4-portal group had a significantly lower morbidity rate of 36.9% than the 2-portal group of 54.1% (P = .02). The rate of major complications that needed reoperation was also significantly lower in the 4-portal group (0%) than the 2-portal group (11.9%) (P = .01). The anastomotic leakage rate was significantly lower in the former (2.8% vs 20.0%, P = .033).
CONCLUSION: The 4-portal technique is a better technique than the 2-portal technique for decreasing postoperative complications in preoperative radiotherapy for rectal cancer.

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Year:  2007        PMID: 17826076     DOI: 10.1016/j.amjsurg.2007.01.030

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  3 in total

1.  Impact of Fluoropyrimidine and Oxaliplatin-based Chemoradiotherapy in Patients With Locally Advanced Rectal Cancer.

Authors:  Yuka Okada; Tsuyoshi Ozawa; Tamuro Hayama; Kohei Ohno; Mitsuo Tsukamoto; Yoshihisa Fukushima; Ryu Shimada; Keijiro Nozawa; Keiji Matsuda; Yojiro Hashiguchi
Journal:  In Vivo       Date:  2021 Jan-Feb       Impact factor: 2.155

2.  Prognostic significance of adverse events associated with preoperative radiotherapy for rectal cancer.

Authors:  Soichiro Ishihara; Toshiaki Watanabe; Takuya Akahane; Ryu Shimada; Atsushi Horiuchi; Hajima Shibuya; Tamuro Hayama; Hideki Yamada; Keijiro Nozawa; Hiroshi Igaki; Keiji Matsuda
Journal:  Int J Colorectal Dis       Date:  2011-02-22       Impact factor: 2.571

3.  Prognostic significance of response to preoperative radiotherapy, lymph node metastasis, and CEA level in patients undergoing total mesorectal excision of rectal cancer.

Authors:  Soichiro Ishihara; Toshiaki Watanabe; Tomomichi Kiyomatsu; Koji Yasuda; Hirokazu Nagawa
Journal:  Int J Colorectal Dis       Date:  2010-09-01       Impact factor: 2.571

  3 in total

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