| Literature DB >> 17825945 |
Tetsuro Suzuki1, Koji Ishii, Hideki Aizaki, Takaji Wakita.
Abstract
Hepatitis C virus (HCV) has been recognized as a major cause of chronic liver diseases worldwide. Molecular studies of the virus became possible with the successful cloning of its genome in 1989. Although much work remains to be done regarding early and late stages of the HCV life cycle, significant progress has been made with respect to the molecular biology of HCV, especially the viral protein processing and the genome replication. This review summarizes our current understanding of genomic organization of HCV, features of the viral protein characteristics, and the viral life cycle.Entities:
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Year: 2007 PMID： 17825945 DOI： 10.1016/j.addr.2007.04.014
Source DB: PubMed Journal: Adv Drug Deliv Rev ISSN： 0169-409X Impact factor: 15.470