Literature DB >> 17822894

Synthesis of 2,3-diaryl-1,3-thiazolidine-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors.

Afshin Zarghi1, Leila Najafnia, Bahram Daraee, Orkideh G Dadrass, Mehdi Hedayati.   

Abstract

A group of 2,3-diaryl-1,3-thiazolidine-4-ones, possessing a methylsulfonyl pharmacophore, were synthesized and their biological activities were evaluated for cyclooxygenase-2 (COX-2) inhibitory activity.

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Year:  2007        PMID： 17822894     DOI： 10.1016/j.bmcl.2007.07.084

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  11 in total

1.  Discovery of new non-acidic lonazolac analogues with COX-2 selectivity as potent anti-inflammatory agents.

Authors:  Marwa F Harras; Rehab Sabour; Omkulthom Mohamed Alkamali
Journal:  Medchemcomm       Date:  2019-07-22       Impact factor: 3.597

2.  Design, synthesis and biological evaluation of new 5,5-diarylhydantoin derivatives as selective cyclooxygenase-2 inhibitors.

Authors:  Afshin Zarghi; Farin Sattary Javid; Razieh Ghodsi; Orkideh G Dadrass; Bahram Daraei; Mehdi Hedayati
Journal:  Sci Pharm       Date:  2011-07-25

3.  Synthesis of novel 3-benzyl-2-phenyl-4(5H)-(substituted phenylhydrazino)-1, 3-oxazolidines and their antihyperglycemic activity.

Authors:  T Panneerselvam
Journal:  J Adv Pharm Technol Res       Date:  2011-01

4.  Design, synthesis and biological evaluation of 5-oxo-1,4,5,6,7,8 hexahydroquinoline derivatives as selective cyclooxygenase-2 inhibitors.

Authors:  Afshin Zarghi; Iman Sabakhi; Vigen Topuzyan; Zahra Hajimahdi; Bahram Daraie
Journal:  Iran J Pharm Res       Date:  2014       Impact factor: 1.696

5.  Selective COX-2 Inhibitors: A Review of Their Structure-Activity Relationships.

Authors:  Afshin Zarghi; Sara Arfaei
Journal:  Iran J Pharm Res       Date:  2011       Impact factor: 1.696

6.  Design, Synthesis and Biological Evaluation of4-(Imidazolylmethyl)-2-(4-methylsulfonyl phenyl)-Quinoline Derivatives as Selective COX-2 Inhibitors and In-vitro Anti-breast Cancer Agents.

Authors:  Razieh Ghodsi; Ebrahim Azizi; Afshin Zarghi
Journal:  Iran J Pharm Res       Date:  2016       Impact factor: 1.696

7.  Design, Synthesis, and Biological Evaluation of New 2-Phenyl-4H-chromen-4-one Derivatives as Selective Cyclooxygenase-2 Inhibitors.

Authors:  Afshin Zarghi; Samaneh Kakhki
Journal:  Sci Pharm       Date:  2014-09-15

8.  Design, Synthesis and Biological Evaluation of New 1, 4-Dihydropyridine (DHP) Derivatives as Selective Cyclooxygenase-2 Inhibitors.

Authors:  Iman Sabakhi; Vigen Topuzyan; Zahra Hajimahdi; Bahram Daraei; Hadi Arefi; Afshin Zarghi
Journal:  Iran J Pharm Res       Date:  2015       Impact factor: 1.696

9.  Design, Synthesis and Biological Evaluation of Novel Peptide-Like Analogues as Selective COX-2 Inhibitors.

Authors:  Mohammad Ali Ahmaditaba; Mohammad Hassan Houshdar Tehrani; Afshin Zarghi; Sorayya Shahosseini; Bahram Daraei
Journal:  Iran J Pharm Res       Date:  2018       Impact factor: 1.696

10.  Physicochemical, Stress Degradation Evaluation and Pharmacokinetic Study of AZGH101; a New Synthesized COX2 Inhibitor after I.V. and Oral Administration in Male and Female Rats.

Authors:  Hoda Bahmanof; Simin Dadashzadeh; Afshin Zarghi; Alireza Shafaati; Seyed Mohsen Foroutan
Journal:  Iran J Pharm Res       Date:  2018       Impact factor: 1.696
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