Husheng Jia1, Wensheng Hou, Liqiao Wei, Bingshe Xu, Xuguang Liu. 1. Key Laboratory of Interface Science and Engineering in Advanced Materials of the Ministry of Education, Taiyuan University of Technology, Taiyuan 030024, China.
Abstract
OBJECTIVES: The aims of this study were to investigate the structures and antibacterial properties of two kinds of sterilizing nano-SiO(2) specimens. METHODS: The specimens were synthesized by adsorption methodology. One of them was synthesized by adsorbing silver cation onto nano-SiO(2) carrier (silver-loading nano-SiO(2) specimen (SLS)), and the other one by co-adsorbing zinc and silver cations onto the same kind of carrier (zinc-silver-loading nano-SiO(2) specimen (SLZS)). Chemical compositions of these specimens were estimated. The structure and morphology of the specimens were determined by X-ray diffraction (XRD) and high-resolution transmission electron microscopy (HRTEM). Also, the antibacterial properties of the specimens were examined. RESULTS: The amount of silver loaded in SLZS was approximate to that of SLS. Consequently, it can be proved that the amount of nano-SiO(2) adsorbed silver cation did not change with the addition of zinc cation. The obvious differences were not observed among the XRD patterns for each specimen. So it was possible to confirm no formation of new phase(s) after Ag(+)/Zn(2+) absorption. The loaded silver and zinc existed as nano-particles, as observed by HRTEM. Antibacterial properties of SLS and SLZS were excellent against Escherichia coli and S. faecalis. The antibacterial effect of the same antibacterial agent against E. coli or S. faecalis was different. In addition, the antibacterial effect of SLZS was better than that of SLS. SIGNIFICANCE: These results suggested SLS and SLZS can be effectively incorporated in dental resin-based materials to provide antibacterial activity against bacteria.
OBJECTIVES: The aims of this study were to investigate the structures and antibacterial properties of two kinds of sterilizing nano-SiO(2) specimens. METHODS: The specimens were synthesized by adsorption methodology. One of them was synthesized by adsorbing silver cation onto nano-SiO(2) carrier (silver-loading nano-SiO(2) specimen (SLS)), and the other one by co-adsorbing zinc and silver cations onto the same kind of carrier (zinc-silver-loading nano-SiO(2) specimen (SLZS)). Chemical compositions of these specimens were estimated. The structure and morphology of the specimens were determined by X-ray diffraction (XRD) and high-resolution transmission electron microscopy (HRTEM). Also, the antibacterial properties of the specimens were examined. RESULTS: The amount of silver loaded in SLZS was approximate to that of SLS. Consequently, it can be proved that the amount of nano-SiO(2) adsorbed silver cation did not change with the addition of zinc cation. The obvious differences were not observed among the XRD patterns for each specimen. So it was possible to confirm no formation of new phase(s) after Ag(+)/Zn(2+) absorption. The loaded silver and zinc existed as nano-particles, as observed by HRTEM. Antibacterial properties of SLS and SLZS were excellent against Escherichia coli and S. faecalis. The antibacterial effect of the same antibacterial agent against E. coli or S. faecalis was different. In addition, the antibacterial effect of SLZS was better than that of SLS. SIGNIFICANCE: These results suggested SLS and SLZS can be effectively incorporated in dental resin-based materials to provide antibacterial activity against bacteria.
Authors: M Prabhu; S Ruby Priscilla; K Kavitha; P Manivasakan; V Rajendran; P Kulandaivelu Journal: Biomed Res Int Date: 2014-09-07 Impact factor: 3.411