| Literature DB >> 17822516 |
Abstract
The pathophysiology of haemophilic synovitis is complex and not as well understood on a molecular level as we have thought. The repeated bleeding episodes and synovial hypertrophy occurring within the joint. Iron and other red-cell debris are phagocytized, and hydrolytic enzymes are produced leading to the destruction of articular cartilage is a simplistic model. However, how iron stimulates this destructive cascade remains speculative and poorly understood. Diagnostic options include radiographic examination using horizontal beam technique, which may reveal a fat blood fluid level, and computed tomography scanning or magnetic resonance imaging.Entities:
Mesh:
Year: 2007 PMID: 17822516 DOI: 10.1111/j.1365-2516.2007.01535.x
Source DB: PubMed Journal: Haemophilia ISSN: 1351-8216 Impact factor: 4.287