| Literature DB >> 17818197 |
Abstract
A simple method is described for producing avirulent mouse brain antigens for complement-fixation tests in human encephalitides, by application of heat at 60 degrees C for 30 minutes. The heated antigens retain for most of the viruses employed a sufficiently high titer to warrant their use, since they are also specific, not anticomplementary, can be lyophilized and moreover, are avirulent, and thus can be handled with safety.Entities:
Year: 1945 PMID： 17818197 DOI： 10.1126/science.102.2659.618
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728