A rebinned backprojection-filtration algorithm for image reconstruction in helical cone-beam CT.

In the last few years, mathematically exact algorithms, including the backprojection-filtration (BPF) algorithm, have been developed for accurate image reconstruction in helical cone-beam CT. The BPF algorithm requires minimum data, and can reconstruct region-of-interest (ROI) images from data containing truncations. However, similar to other existing reconstruction algorithms for helical cone-beam CT, the BPF algorithm involves a backprojection with a spatially varying weighting factor, which is computationally demanding and, more importantly, can lead to undesirable numerical properties in reconstructed images. In this work, we develop a rebinned BPF algorithm in which the backprojection invokes no spatially varying weighting factor for accurate image reconstruction from helical cone-beam projections. This rebinned BPF algorithm is computationally more efficient and numerically more stable than the original BPF algorithm, while it also retains the nice properties of the original BPF algorithm such as minimum data requirement and ROI-image reconstruction from truncated data. We have also performed simulation studies to validate and evaluate the rebinned BPF algorithm.