Literature DB >> 17804144

Who survives from out-of-hospital pulseless electrical activity?

Taneli Väyrynen1, Markku Kuisma, Teuvo Määttä, James Boyd.   

Abstract

AIM OF THE STUDY: To study factors associated with short-term and long-term survival after out-of-hospital cardiac arrest presenting with pulseless electrical activity (PEA).
MATERIALS AND METHODS: This was a retrospective observational study. All out-of-hospital cardiac arrests in Helsinki, Finland during 1 January 1997-31 December 2005 were prospectively registered in the cardiac arrest database. Of 3291 arrests 984 had PEA as the first registered rhythm.
RESULTS: The use of adrenaline was the only factor associated with long-term survival, by increasing mortality. Increasing delay to the return of spontaneous circulation (ROSC) was the only factor associated with survival among patients that survived to admission, also by increasing mortality. There were no survivors that were discharged in overall performance category (OPC) 1-2 after a bystander-witnessed arrest (excluding cases of hypothermia and/or near-drowning) with first responding unit (FRU)-delay over 14 min, or that were resuscitated for more than 20 min. There were no survivors who were discharged in OPC 1-2 after an unwitnessed arrest with the duration of advanced life support (ALS) exceeding 5.5 min.
CONCLUSIONS: The use of adrenaline during resuscitation was the only significant factor which was found to decrease the long-term survival. Among admitted patients, short delay to ROSC was the only factor associated with increased survival. Bystander-CPR and delays to the arrival of the FRU or to the initiation of ALS were not associated with survival. Therefore, it seems difficult to increase survival rates of PEA by improving the chain of survival. More effort should be put to education of the public to call for an ambulance before the cardiac arrest occurs.

Entities:  

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Year:  2007        PMID: 17804144     DOI: 10.1016/j.resuscitation.2007.07.023

Source DB:  PubMed          Journal:  Resuscitation        ISSN: 0300-9572            Impact factor:   5.262


  12 in total

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2.  Therapeutic hypothermia after out-of-hospital cardiac arrest in Finnish intensive care units: the FINNRESUSCI study.

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3.  Survival in out-of-hospital cardiac arrests with initial asystole or pulseless electrical activity and subsequent shockable rhythms.

Authors:  Andrew J Thomas; Craig D Newgard; Rongwei Fu; Dana M Zive; Mohamud R Daya
Journal:  Resuscitation       Date:  2013-02-27       Impact factor: 5.262

4.  Antiarrhythmic Drugs for Nonshockable-Turned-Shockable Out-of-Hospital Cardiac Arrest: The ALPS Study (Amiodarone, Lidocaine, or Placebo).

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Review 5.  Pulseless Electrical Activity: Detection of Underlying Causes in a Prehospital Setting.

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6.  Post resuscitation care of out-of-hospital cardiac arrest patients in the Nordic countries: a questionnaire study.

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7.  Pulseless electrical activity and successful out-of-hospital resuscitation - long-term survival and quality of life: an observational cohort study.

Authors:  Sini Saarinen; Antti Kämäräinen; Tom Silfvast; Arvi Yli-Hankala; Ilkka Virkkunen
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8.  Regional variation and outcome of out-of-hospital cardiac arrest (ohca) in Finland - the Finnresusci study.

Authors:  Pamela Hiltunen; Markku Kuisma; Tom Silfvast; Juha Rutanen; Jukka Vaahersalo; Jouni Kurola
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Review 9.  Effects of prehospital adrenaline administration on out-of-hospital cardiac arrest outcomes: a systematic review and meta-analysis.

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Review 10.  A simplified and structured teaching tool for the evaluation and management of pulseless electrical activity.

Authors:  Laszlo Littmann; Devin J Bustin; Michael W Haley
Journal:  Med Princ Pract       Date:  2013-08-13       Impact factor: 1.927

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