Literature DB >> 1780024

The structural and functional heterogeneity of glutamic acid decarboxylase: a review.

M G Erlander1, A J Tobin.   

Abstract

Studies of the GABA-synthetic enzyme glutamate decarboxylase (glutamic acid decarboxylase; GAD; E.C.4.1.1.15) began in 1951 with the work of Roberts and his colleagues. Since then, many investigators have demonstrated the structural and functional heterogeneity of brain GAD. At least part of this heterogeneity derives from the existence of two GAD genes.

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Year:  1991        PMID： 1780024     DOI： 10.1007/bf00966084

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  102 in total

1.  Transamination of gamma-aminobutyric acid and beta-alanine in brain and liver.

Authors:  E ROBERTS; H M BREGOFF
Journal:  J Biol Chem       Date:  1953-03       Impact factor: 5.157

Review 2.  gamma-Aminobutyric acid outside the mammalian brain.

Authors:  S L Erdö; J R Wolff
Journal:  J Neurochem       Date:  1990-02       Impact factor: 5.372

3.  Kinetics of brain glutamate decarboxylase. Inhibition studies with N-(5'-phosphopyridoxyl) amino acids.

Authors:  A Bayón; L D Possani; R Tapia
Journal:  J Neurochem       Date:  1977-09       Impact factor: 5.372

4.  Stability of synaptosomal GABA levels and their use in determining the in vivo effects of drugs: convulsant agents.

Authors:  J D Wood; M P Russell; E Kurylo; J D Newstead
Journal:  J Neurochem       Date:  1979-07       Impact factor: 5.372

5.  Pyridoxal phosphate and glutamate decarboxylase in subcellular particles of mouse brain and their relationship to convulsions.

Authors:  M Pérez de la Mora; A Feria-Velasco; R Tapia
Journal:  J Neurochem       Date:  1973-06       Impact factor: 5.372

6.  Relationships between pyridoxal phosphate availability, activity of vitamin B 6 -dependent enzymes and convulsions.

Authors:  R Tapia; H Pasantes
Journal:  Brain Res       Date:  1971-06-04       Impact factor: 3.252

Review 7.  Regulatory properties of brain glutamate decarboxylase.

Authors:  D L Martin
Journal:  Cell Mol Neurobiol       Date:  1987-09       Impact factor: 5.046

8.  Comparison of the structures of L-glutamate decarboxylases from human and rat brains.

Authors:  M Maitre; J M Blindermann; L Ossola; P Mandel
Journal:  Biochem Biophys Res Commun       Date:  1978-12-14       Impact factor: 3.575

9.  Metabolic inhibitors and subcellular distribution of GABA.

Authors:  S Sarhan; N Seiler
Journal:  J Neurosci Res       Date:  1979       Impact factor: 4.164

10.  Long term modification of cerebellar inhibition after inferior olive degeneration.

Authors:  C Batini; J M Billard; H Daniel
Journal:  Exp Brain Res       Date:  1985       Impact factor: 1.972
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  88 in total

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Journal:  Neurochem Res       Date:  2002-02       Impact factor: 3.996

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5.  Rapid decrease of GAD 67 content before the convulsion induced by hyperbaric oxygen exposure.

Authors:  Quan Li; Meili Guo; Xiongfei Xu; Xiang Xiao; Weigang Xu; Xuejun Sun; Hengyi Tao; Runping Li
Journal:  Neurochem Res       Date:  2007-08-22       Impact factor: 3.996

6.  Convulsions and inhibition of glutamate decarboxylase by pyridoxal phosphate-gamma-glutamyl hydrazone in the developing rat.

Authors:  L Massieu; A Rivera; R Tapia
Journal:  Neurochem Res       Date:  1994-02       Impact factor: 3.996

7.  Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene.

Authors:  D F Bu; M G Erlander; B C Hitz; N J Tillakaratne; D L Kaufman; C B Wagner-McPherson; G A Evans; A J Tobin
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-15       Impact factor: 11.205

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Authors:  T Yang; S Lev-Yadun; M Feldman; H Fromm
Journal:  Plant Mol Biol       Date:  1998-05       Impact factor: 4.076

9.  Calcium/Calmodulin Activation of Soybean Glutamate Decarboxylase.

Authors:  W. A. Snedden; T. Arazi; H. Fromm; B. J. Shelp
Journal:  Plant Physiol       Date:  1995-06       Impact factor: 8.340

10.  Characterization of two glutamate decarboxylase cDNA clones from Arabidopsis.

Authors:  F J Turano; T K Fang
Journal:  Plant Physiol       Date:  1998-08       Impact factor: 8.340
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