Literature DB >> 17799239

Melatonin Synthesis in the Pineal Gland: Effect of Light Mediated by the Sympathetic Nervous System.

R J Wurtman, J Axelrod, J E Fischer.   

Abstract

Exposure to light reduces the ability of the rat pineal gland to synthesize melatonin and decreases the weight of the gland. When the sympathetic nerves to the pineal gland are cut, light no longer has an effect on melatonin synthesis or pineal weight. The response of the gland does not require that the gonads or the pituitary gland be present.

Entities:  

Year:  1964        PMID： 17799239     DOI： 10.1126/science.143.3612.1328

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  12 in total

1.  CONTROL OF THE CIRCADIAN RHYTHM IN SEROTONIN CONTENT OF THE RAT PINEAL GLAND.

Authors:  S H SNYDER; M ZWEIG; J AXELROD; J E FISCHER
Journal:  Proc Natl Acad Sci U S A       Date:  1965-02       Impact factor: 11.205

2.  EFFECT OF MELATONIN ON SPONTANEOUS CONTRACTIONS AND RESPONSE TO 5-HYDROXYTRYPTAMINE OF RAT ISOLATED DUODENUM.

Authors:  M R QUASTEL; R RAHAMIMOFF
Journal:  Br J Pharmacol Chemother       Date:  1965-04

3.  Melatonin metabolism: neural regulation of pineal serotonin: acetyl coenzyme A N-acetyltransferase activity.

Authors:  D C Klein; J L Weller; R Y Moore
Journal:  Proc Natl Acad Sci U S A       Date:  1971-12       Impact factor: 11.205

4.  Atypical responses to the glucose tolerance test in normal subjects.

Authors:  T Csato
Journal:  Int J Biometeorol       Date:  1968-12       Impact factor: 3.787

5.  Superior cervical ganglionectomy in the Japanese quail.

Authors:  L Z McFarland; K Homma; W O Wilson
Journal:  Experientia       Date:  1968-03-15

6.  Pineal weight response to a dietary variable in Microtus montanus.

Authors:  N C Negus; P J Berger
Journal:  Experientia       Date:  1971-02-15

7.  Evidence for a nonretinal pathway of light to the pineal gland of newborn rats.

Authors:  M Zweig; S H Snyder; J Axelrod
Journal:  Proc Natl Acad Sci U S A       Date:  1966-08       Impact factor: 11.205

8.  Superior cervical ganglionectomy: effect on indolic compounds in rat pineal gland.

Authors:  V S Vassilieff; T L Sourkes; G M Anderson
Journal:  J Neural Transm       Date:  1982       Impact factor: 3.575

9.  Hydroxyindole-O-methyl-transferase activity in the pineal gland of the rabbit.

Authors:  M R de Gallardo; J H Tramezzani
Journal:  J Neural Transm       Date:  1975       Impact factor: 3.575

10.  Circadian profile of serum melatonin in patients with Cushing's syndrome or acromegaly.

Authors:  M Terzolo; A Piovesan; A Alì; A Codegone; A Pia; G Reimondo; M Torta; P Paccotti; G Borretta; A Angeli
Journal:  J Endocrinol Invest       Date:  1995-01       Impact factor: 4.256
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