Literature DB >> 17786824

Cognition in hereditary ataxia.

Katrin Bürk1.   

Abstract

Apart from motor control the cerebellum has been implicated in higher cortical functions such as memory, fronto-executive functions, visuoconstructive skills and emotion. Clinical descriptions of hereditary ataxias mention cognitive impairment to a variable extent. Systematic neuropsychological studies are limited. Regarding the neuropathological pattern in different SCA types, cognitive deficits in hereditary ataxias are not likely to be contingent upon cerebellar degeneration but to result from disruption of cerebrocerebellar circuitries at various levels in the CNS.

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Year:  2007        PMID: 17786824     DOI: 10.1080/14734220601115924

Source DB:  PubMed          Journal:  Cerebellum        ISSN: 1473-4222            Impact factor:   3.648


  99 in total

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  23 in total

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7.  Structural signature in SCA1: clinical correlates, determinants and natural history.

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