Literature DB >> 17786454

[Intracameral application of corticosteroids for treating severe endothelial rejection after penetrating keratoplasty].

F Birnbaum1, P Maier, T Reinhard.   

Abstract

Immune reaction is the main cause for graft failure following penetrating keratoplasty. Endothelial immune reaction is the most frequent and most dangerous subtype of rejection because destruction of the graft endothelium can lead to graft failure. "Acute" endothelial rejection is treated by administration of topical and systemic steroids. Intracameral application of corticosteroids by means of an anterior chamber flush is an adjunctive measure that can stop the immune reaction immediately. This measure is thus recommended in all intermediate and severe endothelial rejections.

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Year:  2007        PMID: 17786454     DOI: 10.1007/s00347-007-1615-9

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  11 in total

Review 1.  Immunologic privilege of the eye.

Authors:  J W Streilein
Journal:  Springer Semin Immunopathol       Date:  1999

Review 2.  [Immunomodulation in penetrating keratoplasty. Current status and perspectives].

Authors:  U Pleyer
Journal:  Ophthalmologe       Date:  2003-12       Impact factor: 1.059

Review 3.  [Immune suppression following perforating keratoplasty].

Authors:  F Birnbaum; A Reis; T Reinhard
Journal:  Ophthalmologe       Date:  2007-05       Impact factor: 1.059

Review 4.  [Systemic immunosuppressives after penetrating keratoplasty].

Authors:  A Reis; F Birnbaum; T Reinhard
Journal:  Ophthalmologe       Date:  2007-05       Impact factor: 1.059

5.  Immune cells in the anterior chamber of patients with immune reactions after penetrating keratoplasty.

Authors:  Thomas Reinhard; Alfred Böcking; Natalia Pomjanski; Rainer Sundmacher
Journal:  Cornea       Date:  2002-01       Impact factor: 2.651

6.  Soluble Fas ligand and transforming growth factor beta2 in the aqueous humor of patients with endothelial immune reactions after penetrating keratoplasty.

Authors:  Thomas Reinhard; Halvard Bönig; Susanne Mayweg; Daniel Böhringer; Ulrich Göbel; Rainer Sundmacher
Journal:  Arch Ophthalmol       Date:  2002-12

7.  Adjunctive intracameral application of corticosteroids in patients with endothelial immune reactions after penetrating keratoplasty: a pilot study.

Authors:  Thomas Reinhard; Rainer Sundmacher
Journal:  Transpl Int       Date:  2002-03-06       Impact factor: 3.782

8.  Improvement of graft prognosis in penetrating normal-risk keratoplasty by HLA class I and II matching.

Authors:  T Reinhard; D Böhringer; J Enczmann; G Kögler; S Mayweg; P Wernet; R Sundmacher
Journal:  Eye (Lond)       Date:  2004-03       Impact factor: 3.775

9.  Long-term results of allogeneic penetrating limbo-keratoplasty in total limbal stem cell deficiency.

Authors:  Thomas Reinhard; Helga Spelsberg; Lotte Henke; Theodoros Kontopoulos; Jürgen Enczmann; Peter Wernet; Peter Berschick; Rainer Sundmacher; Daniel Böhringer
Journal:  Ophthalmology       Date:  2004-04       Impact factor: 12.079

10.  [Clinical aspects and treatment of immune reactions following penetrating normal-risk keratoplasty].

Authors:  N X Nguyen; B Seitz; A Langenbucher; H Wenkel; C Cursiefen
Journal:  Klin Monbl Augenheilkd       Date:  2004-06       Impact factor: 0.700

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