Literature DB >> 17779974

Purine resistant mutants of Drosophila are adenine phosphoribosyltransferase deficient.

D H Johnson, T B Friedman.   

Abstract

A deficiency for adenine phosphoribosyltransferase activity is the primary biochemical defect in mutants of Drosophila selected for resistance to purine-induced lethality.

Entities:  

Year:  1981        PMID: 17779974     DOI: 10.1126/science.212.4498.1035

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  4 in total

1.  The PurR mutation of Drosophila melanogaster confers resistance to purine and 2,6-diaminopurine by elevating adenosine deaminase activity.

Authors:  F L Dutton; A Chovnick
Journal:  Mol Gen Genet       Date:  1990-01

2.  In vitro suppression of a nonsense mutant of Drosophila melanogaster.

Authors:  E Kubli; T Schmidt; P F Martin; W Sofer
Journal:  Nucleic Acids Res       Date:  1982-11-25       Impact factor: 16.971

3.  Adenine phosphoribosyltransferase genes in two Drosophila species: dosage compensation, a nuclear matrix attachment site, and a novel intron position.

Authors:  D H Johnson
Journal:  Mol Gen Genet       Date:  1993-04

4.  Purine-resistant Drosophila melanogaster result from mutations in the adenine phosphoribosyltransferase structural gene.

Authors:  D H Johnson; T B Friedman
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

  4 in total

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