Literature DB >> 17779440

Breaking the diffraction barrier: optical microscopy on a nanometric scale.

E Betzig, J K Trautman, T D Harris, J S Weiner, R L Kostelak.   

Abstract

In near-field scanning optical microscopy, a light source or detector with dimensions less than the wavelength (lambda) is placed in close proximity (lambda/50) to a sample to generate images with resolution better than the diffraction limit. A near-field probe has been developed that yields a resolution of approximately 12 nm ( approximately lambda/43) and signals approximately 10(4)- to 10(6)-fold larger than those reported previously. In addition, image contrast is demonstrated to be highly polarization dependent. With these probes, near-field microscopy appears poised to fulfill its promise by combining the power of optical characterization methods with nanometric spatial resolution.

Year:  1991        PMID: 17779440     DOI: 10.1126/science.251.5000.1468

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  58 in total

1.  A model for membrane patchiness: lateral diffusion in the presence of barriers and vesicle traffic.

Authors:  L A Gheber; M Edidin
Journal:  Biophys J       Date:  1999-12       Impact factor: 4.033

Review 2.  Nanofabrication for the analysis and manipulation of membranes.

Authors:  Christopher V Kelly; Harold G Craighead
Journal:  Ann Biomed Eng       Date:  2011-12-06       Impact factor: 3.934

Review 3.  Electron microscopy of specimens in liquid.

Authors:  Niels de Jonge; Frances M Ross
Journal:  Nat Nanotechnol       Date:  2011-10-23       Impact factor: 39.213

4.  Sparsity-based single-shot subwavelength coherent diffractive imaging.

Authors:  A Szameit; Y Shechtman; E Osherovich; E Bullkich; P Sidorenko; H Dana; S Steiner; E B Kley; S Gazit; T Cohen-Hyams; S Shoham; M Zibulevsky; I Yavneh; Y C Eldar; O Cohen; M Segev
Journal:  Nat Mater       Date:  2012-04-01       Impact factor: 43.841

5.  Simultaneous two color image capture for sub-diffraction localization fluorescence microscopy.

Authors:  Ben J Glasgow; Lie Ma
Journal:  Micron       Date:  2015-09-11       Impact factor: 2.251

6.  Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping.

Authors:  Ken Y Chan; Nicholas C Flytzanis; Bin Yang; Jennifer B Treweek; Benjamin E Deverman; Alon Greenbaum; Antti Lignell; Cheng Xiao; Long Cai; Mark S Ladinsky; Pamela J Bjorkman; Charless C Fowlkes; Viviana Gradinaru
Journal:  Nat Protoc       Date:  2015-10-22       Impact factor: 13.491

7.  High-resolution near-field optical imaging of single nuclear pore complexes under physiological conditions.

Authors:  C Höppener; J P Siebrasse; R Peters; U Kubitscheck; A Naber
Journal:  Biophys J       Date:  2005-02-04       Impact factor: 4.033

Review 8.  The evolution and future of minimalism in neurological surgery.

Authors:  Charles Y Liu; Michael Y Wang; Michael L J Apuzzo
Journal:  Childs Nerv Syst       Date:  2004-07-30       Impact factor: 1.475

9.  Lateral resolution enhancement with standing evanescent waves.

Authors:  G E Cragg; P T So
Journal:  Opt Lett       Date:  2000-01-01       Impact factor: 3.776

10.  Altering the biochemical state of individual cultured cells and organelles with ultramicroelectrodes.

Authors:  J A Lundqvist; F Sahlin; M A Aberg; A Strömberg; P S Eriksson; O Orwar
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-01       Impact factor: 11.205

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