Literature DB >> 17768123

Lactadherin mediates sickle cell adhesion to vascular endothelial cells in flowing blood.

Prasenjit Guchhait, Swapan K Dasgupta, Anhquyen Le, Sarvari Yellapragada, José A López, Perumal Thiagarajan.   

Abstract

Increased exposure of sickle red blood cells to phosphatidylserine promotes its adhesion to the endothelium. A monoclonal antibody to lactadherin, a phosphatidylserine binding protein, inhibits sickle cell adhesion to histamine-stimulated endothelial cells in flowing blood. Added lactadherin enhances the adhesion via the integrin alphaVbeta3. These results indicate that lactadherin can mediate phosphatidylserine-expressing sickle cell adhesion to the endothelium.

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Year:  2007        PMID: 17768123     DOI: 10.3324/haematol.11379

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


  9 in total

1.  Phosphatidylethanolamine is progressively exposed in RBCs during storage.

Authors:  M C Larson; M S Karafin; C A Hillery; N Hogg
Journal:  Transfus Med       Date:  2017-01-30       Impact factor: 2.019

2.  Stored red blood cell susceptibility to in vitro transfusion-associated stress conditions is higher after longer storage and increased by storage in saline-adenine-glucose-mannitol compared to AS-1.

Authors:  Diana Mittag; Amrita Sran; Kasey S Chan; Martin P Boland; Esther Bandala-Sanchez; Olivier Huet; William Xu; Rosemary L Sparrow
Journal:  Transfusion       Date:  2015-05-13       Impact factor: 3.157

3.  Specific binding of red blood cells to endothelial cells is regulated by nonadsorbing macromolecules.

Authors:  Yang Yang; Stephanie Koo; Cheryl Shuyi Lin; Björn Neu
Journal:  J Biol Chem       Date:  2010-10-15       Impact factor: 5.157

4.  Biomechanical aspects of the auto-digestion theory.

Authors:  Geert W Schmid-Schönbein
Journal:  Mol Cell Biomech       Date:  2008-06

5.  Inflammation in sickle cell disease.

Authors:  Nicola Conran; John D Belcher
Journal:  Clin Hemorheol Microcirc       Date:  2018       Impact factor: 2.375

6.  Lactadherin and clearance of platelet-derived microvesicles.

Authors:  Swapan K Dasgupta; Hanan Abdel-Monem; Polly Niravath; Anhquyen Le; Ricardo V Bellera; Kimberly Langlois; Shigekazu Nagata; Rolando E Rumbaut; Perumal Thiagarajan
Journal:  Blood       Date:  2008-11-20       Impact factor: 22.113

7.  Role of extracellular hemoglobin in thrombosis and vascular occlusion in patients with sickle cell anemia.

Authors:  Zhou Zhou; Molly Behymer; Prasenjit Guchhait
Journal:  Anemia       Date:  2010-12-27

8.  Evaluation of inhibition of F4ac positive Escherichia coli attachment with xanthine dehydrogenase, butyrophilin, lactadherin and fatty acid binding protein.

Authors:  Predrag Novakovic; Chandrashekhar Charavaryamath; Igor Moshynskyy; Betty Lockerbie; Radhey S Kaushik; Matthew E Loewen; Beverly A Kidney; Chris Stuart; Elemir Simko
Journal:  BMC Vet Res       Date:  2015-09-15       Impact factor: 2.741

Review 9.  Red Blood Cells: Chasing Interactions.

Authors:  Virginia Pretini; Mischa H Koenen; Lars Kaestner; Marcel H A M Fens; Raymond M Schiffelers; Marije Bartels; Richard Van Wijk
Journal:  Front Physiol       Date:  2019-07-31       Impact factor: 4.566

  9 in total

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