| Literature DB >> 17767196 |
Abstract
The translation of many proteins involved in transcription, cell cycle progression, apoptosis and cell survival is mediated by internal ribosome entry sites (IRESs) present within the 5'-untranslated regions (5'-UTRs) of their messenger RNA molecules (mRNAs). Several recent reports now demonstrate that the proteins controlling IRES-dependent translation initiation are regulated by their subcellular localization.Mesh:
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Year: 2007 PMID: 17767196 DOI: 10.1038/sj.onc.1210777
Source DB: PubMed Journal: Oncogene ISSN: 0950-9232 Impact factor: 9.867