Literature DB >> 17766503

Routine immunization practices: use of topical anesthetics and oral analgesics.

Anna Taddio1, Jennifer Manley, Leah Potash, Moshe Ipp, Michael Sgro, Vibhuti Shah.   

Abstract

BACKGROUND: Immunization pain is a global public health issue. Despite an abundance of data that demonstrate the efficacy of local anesthetics for decreasing immunization pain, their adoption in practice has not been determined. Our objective was to evaluate analgesic use during childhood immunization. PATIENTS AND METHODS: We used a cluster-sampling survey of pediatricians in the greater Toronto area (who administer immunizations) and multiparous women. By using a self-administered survey, pediatricians reported frequency of analgesic use in their practice for 2 phases of immunization: injection (needle puncture and vaccine administration) and postinjection (hours to days postvaccination). By using an interviewer-administered face-to-face survey, mothers reported analgesic practices for their children.
RESULTS: Of 195 eligible pediatricians, 140 (72%) responded. During the injection phase, 58% rarely or never used analgesics compared with 11% for the postinjection phase. During injection, the local anesthetics lidocaine-prilocaine and tetracaine were used at least sometimes in 12% and 2% of the practices, respectively, whereas acetaminophen and ibuprofen were used in 81% and 46%, respectively. Postinjection, acetaminophen and ibuprofen were used in 89% and 56% of practices. Of 257 eligible mothers, 200 (78%) participated. During injection, analgesics were used in 25% of immunizations (acetaminophen [87%], ibuprofen [7%], and lidocaine-prilocaine [6%]). Postinjection, analgesics were used in 33% of immunizations (acetaminophen [86%] and ibuprofen [14%]).
CONCLUSIONS: A minority of pediatricians and mothers use topical local anesthetics during childhood immunization despite evidence to support their use. Oral analgesics are used more commonly, but this practice is not consistent with scientific evidence. Knowledge-translation strategies are needed to increase the use of local anesthesia.

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Year:  2007        PMID: 17766503     DOI: 10.1542/peds.2006-3351

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  28 in total

Review 1.  Reducing the pain of childhood vaccination: an evidence-based clinical practice guideline (summary).

Authors:  Anna Taddio; Mary Appleton; Robert Bortolussi; Christine Chambers; Vinita Dubey; Scott Halperin; Anita Hanrahan; Moshe Ipp; Donna Lockett; Noni MacDonald; Deana Midmer; Patricia Mousmanis; Valerie Palda; Karen Pielak; Rebecca Pillai Riddell; Michael Rieder; Jeffrey Scott; Vibhuti Shah
Journal:  CMAJ       Date:  2010-11-22       Impact factor: 8.262

Review 2.  Reducing the pain of childhood vaccination: an evidence-based clinical practice guideline.

Authors:  Anna Taddio; Mary Appleton; Robert Bortolussi; Christine Chambers; Vinita Dubey; Scott Halperin; Anita Hanrahan; Moshe Ipp; Donna Lockett; Noni MacDonald; Deana Midmer; Patricia Mousmanis; Valerie Palda; Karen Pielak; Rebecca Pillai Riddell; Michael Rieder; Jeffrey Scott; Vibhuti Shah
Journal:  CMAJ       Date:  2010-11-22       Impact factor: 8.262

3.  Reducing pain during vaccine injections: clinical practice guideline.

Authors:  Anna Taddio; C Meghan McMurtry; Vibhuti Shah; Rebecca Pillai Riddell; Christine T Chambers; Melanie Noel; Noni E MacDonald; Jess Rogers; Lucie M Bucci; Patricia Mousmanis; Eddy Lang; Scott A Halperin; Susan Bowles; Christine Halpert; Moshe Ipp; Gordon J G Asmundson; Michael J Rieder; Kate Robson; Elizabeth Uleryk; Martin M Antony; Vinita Dubey; Anita Hanrahan; Donna Lockett; Jeffrey Scott; Elizabeth Votta Bleeker
Journal:  CMAJ       Date:  2015-08-24       Impact factor: 8.262

Review 4.  Effect of antipyretic analgesics on immune responses to vaccination.

Authors:  Ezzeldin Saleh; M Anthony Moody; Emmanuel B Walter
Journal:  Hum Vaccin Immunother       Date:  2016-05-31       Impact factor: 3.452

5.  Pharmacists as vaccinators: An analysis of their experiences and perceptions of their new role.

Authors:  Sandra Gerges; Elizabeth Peter; Susan K Bowles; Shelley Diamond; Lucie Marisa Bucci; Anne Resnick; Anna Taddio
Journal:  Hum Vaccin Immunother       Date:  2017-12-19       Impact factor: 3.452

6.  Children's Pain and Distress at a Public Influenza Vaccination Clinic: A Parent Survey and Public Observation Study.

Authors:  Imane Ouach; Jessica Reszel; Yesha Patel; JoAnne Tibbles; Nora Ullyot; Jodi Wilding; Denise Harrison
Journal:  J Community Health       Date:  2019-04

7.  Parental Approach to the Prevention and Management of Fever and Pain Following Childhood Immunizations: A Survey Study.

Authors:  Ezzeldin Saleh; Geeta K Swamy; M Anthony Moody; Emmanuel B Walter
Journal:  Clin Pediatr (Phila)       Date:  2016-10-23       Impact factor: 1.168

Review 8.  Breastfeeding for procedural pain in infants beyond the neonatal period.

Authors:  Denise Harrison; Jessica Reszel; Mariana Bueno; Margaret Sampson; Vibhuti S Shah; Anna Taddio; Catherine Larocque; Lucy Turner
Journal:  Cochrane Database Syst Rev       Date:  2016-10-28

Review 9.  Strategies for the prevention and management of neonatal and infant pain.

Authors:  Denise Harrison; Janet Yamada; Bonnie Stevens
Journal:  Curr Pain Headache Rep       Date:  2010-04

10.  Bringing Parent Voices into a Pediatric Research Network Through a Virtual Parent Panel.

Authors:  Stacey A Engster; Carrie Fascetti; Alexandra Mykita; Kate Pompa; Evelyn Cohen Reis
Journal:  J Am Board Fam Med       Date:  2020 Sep-Oct       Impact factor: 2.657

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