Literature DB >> 17765858

Bilateral familial Duane's retraction syndrome.

Lily Y Zhu-Tam1, Andrew S Gurwood.   

Abstract

BACKGROUND: Duane's retraction syndrome (DRS) is a congenital oculomotor anomaly that is accompany by globe retraction with simultaneous narrowing of the palpebral fissure on attempted adduction. Hereditary factors have been postulated to be associated with the development of DRS since 1879. However, the modern literature fails to provide substantial scientific evidence to support this premise. CASE REPORT: A 7-year-old patient presented with bilateral abduction deficit and retraction of the globe with narrowing of the palpebral fissure on attempted adduction.
CONCLUSION: We present a case of Duane's retraction syndrome in which an investigation of the family history uncovered 4 generations of affected family members, lending support to the theory that some cases of DRS are inherited.

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Year:  2007        PMID: 17765858     DOI: 10.1016/j.optm.2007.03.014

Source DB:  PubMed          Journal:  Optometry        ISSN: 1558-1527


  1 in total

1.  Two novel CHN1 mutations in 2 families with Duane retraction syndrome.

Authors:  Wai-Man Chan; Noriko Miyake; Lily Zhu-Tam; Caroline Andrews; Elizabeth C Engle
Journal:  Arch Ophthalmol       Date:  2011-05
  1 in total

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