Literature DB >> 17765816

Steroids for deteriorating herpes simplex virus encephalitis.

Banan Musallam1, Israel Matoth, Dana G Wolf, Dan Engelhard, Diana Averbuch.   

Abstract

A 16-month-old girl presented with herpes simplex virus type 1 encephalitis with involvement of bilateral parietofrontal lobes, left thalamus and cerebellum. She was treated with intravenous acyclovir. As her condition deteriorated, high-dose methylprednisolone was administered, resulting in remarkable improvement. This case suggests considering a short course of high-dose steroid therapy in severe herpes simplex encephalitis when there is clinical and radiologic deterioration in spite of appropriate antiviral therapy and decreasing viral load in the cerebrospinal fluid.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17765816     DOI： 10.1016/j.pediatrneurol.2007.05.007

Source DB:  PubMed          Journal:  Pediatr Neurol        ISSN： 0887-8994            Impact factor:   3.372


  7 in total

1.  Poor neurological sequelae of herpes simplex virus encephalitis in an infant despite adequate antiviral and adjunct corticosteroid therapy.

Authors:  Ratna B Basak; Varsha Malpani; Khalid Kakish; Susan Vargese; Nageshwar Chauhan; Andreas Boeck
Journal:  Indian J Dermatol       Date:  2011-11       Impact factor: 1.494

2.  Herpesvirus infections of the central nervous system in immunocompromised patients.

Authors:  Uta Meyding-Lamadé; Cornelia Strank
Journal:  Ther Adv Neurol Disord       Date:  2012-09       Impact factor: 6.570

Review 3.  Immunomodulatory Strategies in Herpes Simplex Virus Encephalitis.

Authors:  Jocelyne Piret; Guy Boivin
Journal:  Clin Microbiol Rev       Date:  2020-02-12       Impact factor: 26.132

4.  Microglia are the major cellular source of inducible nitric oxide synthase during experimental herpes encephalitis.

Authors:  Cristina P Marques; Maxim C-J Cheeran; Joseph M Palmquist; Shuxian Hu; James R Lokensgard
Journal:  J Neurovirol       Date:  2008-05       Impact factor: 2.643

Review 5.  Herpes simplex type I (HSV-1) infection of the nervous system: is an immune response a good thing?

Authors:  Christopher D Conrady; Douglas A Drevets; Daniel J J Carr
Journal:  J Neuroimmunol       Date:  2009-10-09       Impact factor: 3.478

6.  Prolonged microglial cell activation and lymphocyte infiltration following experimental herpes encephalitis.

Authors:  Cristina P Marques; Maxim C-J Cheeran; Joseph M Palmquist; Shuxian Hu; Stina L Urban; James R Lokensgard
Journal:  J Immunol       Date:  2008-11-01       Impact factor: 5.422

7.  Protocol for DexEnceph: a randomised controlled trial of dexamethasone therapy in adults with herpes simplex virus encephalitis.

Authors:  Thomas Whitfield; Cristina Fernandez; Kelly Davies; Sylviane Defres; Michael Griffiths; Cory Hooper; Rebecca Tangney; Girvan Burnside; Anna Rosala-Hallas; Perry Moore; Kumar Das; Mark Zuckerman; Laura Parkes; Simon Keller; Neil Roberts; Ava Easton; Saber Touati; Rachel Kneen; J P Stahl; Tom Solomon
Journal:  BMJ Open       Date:  2021-07-22       Impact factor: 2.692
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.