| Literature DB >> 17765673 |
Ghassan Mouneimne1, Joan S Brugge.
Abstract
Epidermal Growth Factor (EGF) is an important regulator of normal epithelial and carcinoma cell migration. The mechanism by which EGF induces cell migration is not fully understood. A recent report in Nature Cell Biology (Katz et al., 2007) demonstrates that EGF regulates migration through a switch in the expression of two tensin isoforms, weakening the association of beta1 integrin with the actin cytoskeleton in focal adhesions.Entities:
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Year: 2007 PMID: 17765673 DOI: 10.1016/j.devcel.2007.08.010
Source DB: PubMed Journal: Dev Cell ISSN: 1534-5807 Impact factor: 12.270