| Literature DB >> 17764704 |
Beatrice Nico1, Domenica Mangieri, Vincenzo Benagiano, Enrico Crivellato, Domenico Ribatti.
Abstract
Nerve growth factor (NGF), a neurotrophin that plays a crucial role in promoting neurotrophic and neurotropic effects in sympathetic neurons, has recently been identified as a novel angiogenic molecule, which exerts a variety of effects in the cardiovascular system and on endothelial cells. In fact, NGF may contribute to maintenance, survival, and function of endothelial cells by autocrine and/or paracrine mechanisms. This review summarizes the involvement of NGF in the regulation of angiogenesis in both normal and pathological conditions.Entities:
Mesh:
Substances:
Year: 2007 PMID: 17764704 DOI: 10.1016/j.mvr.2007.07.004
Source DB: PubMed Journal: Microvasc Res ISSN: 0026-2862 Impact factor: 3.514