K L Spence1, D Murphy, C Kilian, R McGonigle, R A Kilani. 1. Division of Newborn Medicine, the Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St Louis Children's Hospital, St Louis, MO, USA. spence_k@kids.wustle.edu
Abstract
OBJECTIVE: To measure the intrapharyngeal pressure (IPP) generated by high-flow nasal cannula (HFNC) at varying flow rates up to 5 l min(-1). STUDY DESIGN: We studied 14 infants on HFNC or NCPAP using IPP manometry to measure the IPP generated at flows of 1, 2, 3, 4 and 5 l min(-1). RESULT: On average flow rates of 1, 2, 3, 4 and 5 l min(-1) generated an IPP (cm of H(2)O) of 1.70+/-0.34, 1.75+/-0.2, 2.62+/-0.28, 3.78+/-0.44 and 4.84+/-0.51 respectively. CONCLUSION: HFNC delivers significant IPP and is potentially a well-tolerated and viable option to provide CPAP at flows of > or = 3 min(-1) in infants with respiratory distress.
OBJECTIVE: To measure the intrapharyngeal pressure (IPP) generated by high-flow nasal cannula (HFNC) at varying flow rates up to 5 l min(-1). STUDY DESIGN: We studied 14 infants on HFNC or NCPAP using IPP manometry to measure the IPP generated at flows of 1, 2, 3, 4 and 5 l min(-1). RESULT: On average flow rates of 1, 2, 3, 4 and 5 l min(-1) generated an IPP (cm of H(2)O) of 1.70+/-0.34, 1.75+/-0.2, 2.62+/-0.28, 3.78+/-0.44 and 4.84+/-0.51 respectively. CONCLUSION: HFNC delivers significant IPP and is potentially a well-tolerated and viable option to provide CPAP at flows of > or = 3 min(-1) in infants with respiratory distress.
Authors: A Schibler; T M T Pham; K R Dunster; K Foster; A Barlow; K Gibbons; J L Hough Journal: Intensive Care Med Date: 2011-03-03 Impact factor: 17.440
Authors: Meg Frizzola; Thomas L Miller; Maria Elena Rodriguez; Yan Zhu; Jorge Rojas; Anne Hesek; Angela Stump; Thomas H Shaffer; Kevin Dysart Journal: Pediatr Pulmonol Date: 2010-11-23
Authors: B E de Jongh; R Locke; A Mackley; J Emberger; D Bostick; J Stefano; E Rodriguez; T H Shaffer Journal: J Perinatol Date: 2013-09-26 Impact factor: 2.521