Literature DB >> 17747919

Toward protein tertiary structure recognition by means of associative memory hamiltonians.

M S Friedrichs, P G Wolynes.   

Abstract

The statistical mechanics of associative memories and spin glasses suggests ways to design Hamiltonians for protein folding. An associative memory Hamiltonian based on hydrophobicity patterns is shown to have a large capacity for recall and to be capable of recognizing tertiary structure for moderately variant sequences.

Entities:  

Year:  1989        PMID： 17747919     DOI： 10.1126/science.246.4928.371

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  35 in total

1.  Associative memory hamiltonians for structure prediction without homology: alpha-helical proteins.

Authors:  C Hardin; M P Eastwood; Z Luthey-Schulten; P G Wolynes
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-19       Impact factor: 11.205

2.  Protein threading by learning.

Authors:  I Chang; M Cieplak; R I Dima; A Maritan; J R Banavar
Journal:  Proc Natl Acad Sci U S A       Date:  2001-11-20       Impact factor: 11.205

3.  Associative memory Hamiltonians for structure prediction without homology: alpha/beta proteins.

Authors:  Corey Hardin; Michael P Eastwood; Michael C Prentiss; Zadia Luthey-Schulten; Peter G Wolynes
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-28       Impact factor: 11.205

4.  Protein tertiary structure recognition using optimized Hamiltonians with local interactions.

Authors:  R A Goldstein; Z A Luthey-Schulten; P G Wolynes
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-01       Impact factor: 11.205

5.  An algorithm for protein engineering: simulations of recursive ensemble mutagenesis.

Authors:  A P Arkin; D C Youvan
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-15       Impact factor: 11.205

6.  Optimal protein-folding codes from spin-glass theory.

Authors:  R A Goldstein; Z A Luthey-Schulten; P G Wolynes
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-01       Impact factor: 11.205

7.  A funneled energy landscape for cytochrome c directly predicts the sequential folding route inferred from hydrogen exchange experiments.

Authors:  Patrick Weinkam; Chenghang Zong; Peter G Wolynes
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-22       Impact factor: 11.205

8.  A strategy for finding classes of minima on a hypersurface: implications for approaches to the protein folding problem.

Authors:  T Head-Gordon; F H Stillinger; J Arrecis
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-15       Impact factor: 11.205

9.  Nonequilibrium landscape theory of neural networks.

Authors:  Han Yan; Lei Zhao; Liang Hu; Xidi Wang; Erkang Wang; Jin Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2013-10-21       Impact factor: 11.205

10.  Binding of NFκB Appears to Twist the Ankyrin Repeat Domain of IκBα.

Authors:  Morten Beck Trelle; Kristen M Ramsey; Taehyung C Lee; Weihua Zheng; Jorge Lamboy; Peter G Wolynes; Ashok Deniz; Elizabeth A Komives
Journal:  Biophys J       Date:  2016-02-23       Impact factor: 4.033
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.