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Literature DB >> 1774401

Oxalate-induced encephalitis after infusions of sugar surrogates.

N Heye¹, C Zimmer, K Terstegge, C Sirtl, J Cervós-Navarro.

Abstract

The case of a 55-year-old female with oxalate-induced lethal encephalitis following infusions of sugar surrogates is reported. Renal failure and subsequent central coma developed following the use of xylitol, fructose and sorbitol above the recommended dosages. The patient died due to raised intracranial pressure. Cerebral damage was caused by encephalitis due to calcium oxalate crystals. Oxalosis induced by sugar surrogates may be explained either by dose-dependent toxic effects or genetically fixed intolerance.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1991 PMID： 1774401 DOI： 10.1007/bf01720685

Source DB: PubMed Journal: Intensive Care Med ISSN： 0342-4642 Impact factor: 17.440

11 in total

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Authors: N Lameire; M Mussche; G Baele; J Kint; S Ringoir
Journal: Am J Med Date: 1978-09 Impact factor: 4.965

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Authors: R G Galaske; M Burdelski; J Brodehl
Journal: Dtsch Med Wochenschr Date: 1986-06-20 Impact factor: 0.628

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Authors: G Berg; F Matzkies; H Bickel
Journal: Dtsch Med Wochenschr Date: 1974-03-29 Impact factor: 0.628

4. Mechanism of xylitol toxicity in the rabbit.

Authors: Y M Wang; S M King; J H Patterson; J Van Eys
Journal: Metabolism Date: 1973-07 Impact factor: 8.694

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Authors: H Talke; K P Maier
Journal: Infusionstherapie Date: 1973-10

6. [Metabolic investigations during continuous infusion of glucose, fructose, and xylitol over 48 hours (author's transl)].

Authors: H Förster; L Heller; U Hellmund
Journal: Dtsch Med Wochenschr Date: 1974-08-30 Impact factor: 0.628

Oxalate-induced encephalitis after infusions of sugar surrogates.

1. Hereditary fructose intolerance: a difficult diagnosis in the adult.

2. [Primary polyuric kidney failure and acute yellow liver dystrophy following infusion of glucose substitutes in children].

3. [Infusion dose limits of glucose, sorbitol, fructose xylitol and their mixtures (author's transl)].

4. Mechanism of xylitol toxicity in the rabbit.

5. [Glucose, fructose, sorbitol and xylitol metabolism in man].

6. [Metabolic investigations during continuous infusion of glucose, fructose, and xylitol over 48 hours (author's transl)].

7. Oxalate-induced encephalitic reactions to polyol-containing infusions during intensive care.

8. [Clinical aspects of oxalate metabolism].

9. Nerve glucose, fructose, sorbitol, myo-inositol, and fiber degeneration and regeneration in diabetic neuropathy.

10. The isolation and characterization of Ca++-accumulating subcellular membrane fractions from cerebral arteries.

1. Fatal cerebro-renal oxalosis after appendectomy.

2. Secondary oxalosis induced by xylitol concurrent with lithium-induced nephrogenic diabetes insipidus: a case report.