Literature DB >> 1774093

Adverse foetal outcome in specific IgM positive Chlamydia trachomatis infection in pregnancy.

A Jain1, V L Nag, M M Goel, U C Chaturvedi.   

Abstract

A study was undertaken to determine the adverse foetal outcome in antichlamydial IgM positive asymptomatic pregnant females. An indirect immunoperoxidase assay was done to detect IgM in 78 apparently normal asymptomatic pregnant women during the third trimester and follow up was done till delivery to study the effect of chlamydial infection on foetal outcome. A total of 28 (35.9%) women were positive for antichlamydial IgM while only 3.33 per cent asymptomatic non-pregnant normal women (controls) were positive. 28.7 per cent IgM positive mothers delivered low birth weight (LBW) babies (P less than 0.05), 9.7 per cent had premature labour (PTL) and 4.7 per cent had intrauterine death (IUD). The findings are significant as none of the IgM negative mothers had PTL and IUD and only 2.6 per cent had LBW babies.

Entities:  

Keywords:  Age Factors; Asia; Biology; Birth Weight; Body Weight; Case Control Studies; Chlamydia; Demographic Factors; Developing Countries; Diseases; Examinations And Diagnoses; Fetal Death--etiology; Hematologic Tests; India; Infant; Infant, Premature--etiology; Infections; Laboratory Examinations And Diagnoses; Laboratory Procedures; Low Birth Weight--etiology; Methodological Studies; Mortality; Physiology; Population; Population Characteristics; Population Dynamics; Pregnancy; Pregnancy Outcomes; Reproduction; Reproductive Tract Infections; Research Methodology; Sexually Transmitted Diseases; Southern Asia; Studies; Youth

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Substances:

Year:  1991        PMID: 1774093

Source DB:  PubMed          Journal:  Indian J Med Res        ISSN: 0971-5916            Impact factor:   2.375


  5 in total

1.  Chlamydia trachomatis infection modulates trophoblast cytokine/chemokine production.

Authors:  Eugenia de la Torre; Melissa J Mulla; Andrew G Yu; Seung-Joon Lee; Paula B Kavathas; Vikki M Abrahams
Journal:  J Immunol       Date:  2009-03-15       Impact factor: 5.422

2.  Functional expression of pattern recognition receptors in tissues of the human female reproductive tract.

Authors:  Kevin M Hart; Amy J Murphy; Karlene T Barrett; Charles R Wira; Paul M Guyre; Patricia A Pioli
Journal:  J Reprod Immunol       Date:  2009-04-29       Impact factor: 4.054

3.  Chlamydia trachomatis and Adverse Pregnancy Outcomes: Meta-analysis of Patients With and Without Infection.

Authors:  Courtney Olson-Chen; Kripa Balaram; David N Hackney
Journal:  Matern Child Health J       Date:  2018-06

4.  Expression of Toll-like receptors 7-10 in human fallopian tubes.

Authors:  Nasrin Ghasemi; Fatemehsadat Amjadi; Ensieh Salehi; Mojgan Shakeri; Abbas Aflatoonian; Reza Aflatoonian
Journal:  Iran J Reprod Med       Date:  2014-06

Review 5.  Chlamydia trachomatis Infection in Pregnancy: The Global Challenge of Preventing Adverse Pregnancy and Infant Outcomes in Sub-Saharan Africa and Asia.

Authors:  Kristina Adachi; Karin Nielsen-Saines; Jeffrey D Klausner
Journal:  Biomed Res Int       Date:  2016-04-06       Impact factor: 3.411

  5 in total

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