Literature DB >> 17738028

INHIBITION OF beta HEMOLYTIC STREPTOCOCCI FIBRINOLYSIN BY TRYPSIN INHIBITOR (ANTIPROTEASE).

I A Mirsky.   

Abstract

Crystalline "trypsin-inhibitor" of pancreatic origin and the antitrypsin of soybean origin completely inhibit the fibrinolytic activity of cultures of beta hemolytic streptococci, of filtrates of such cultures and of concentrates of such filtrates. It is suggested that the streptococcal fibrinolysin is a protease and that it may be related to trypsin. The author wishes to acknowledge gratefully the cooperation of Lieutenant Colonel Robert L. King, Lieutenant Colonel E. D. Embree and Captain Edward Freis.

Entities:  

Year:  1944        PMID： 17738028     DOI： 10.1126/science.100.2592.198

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  11 in total

1.  STUDIES OF STREPTOCOCCAL FIBRINOLYSIS. II. THE INHIBITION OF STREPTOCOCCAL FIBRINOLYSIS BY ANTIFIBRINOLYSIN AND ANTIPROTEASE.

Authors:  M H Kaplan
Journal:  J Clin Invest       Date:  1946-05       Impact factor: 14.808

2.  STUDIES OF STREPTOCOCCAL FIBRINOLYSIS. I. THE DISSIMILARITY OF SERUM PROTEASE AND TRYPSIN AS INDICATED BY THE SEPARATE SPECIFICITIES OF THEIR KINASES, FIBRINOLYSIN AND ENTEROKINASE.

Authors:  M H Kaplan
Journal:  J Clin Invest       Date:  1946-05       Impact factor: 14.808

3.  Antifibrinolytic Therapy.

Authors:  W H Manwaring
Journal:  Cal West Med       Date:  1945-02

4.  Studies on a proteolytic enzyme in human plasma. VII. A fatal hemorrhagic state associated with excessive plasma proteolytic activity in a patient undergoing surgery for carcinoma of the head of the pancreas.

Authors:  O D RATNOFF
Journal:  J Clin Invest       Date:  1952-05       Impact factor: 14.808

5.  C1 inactivator inhibition by plasmin.

Authors:  P C Harpel
Journal:  J Clin Invest       Date:  1970-03       Impact factor: 14.808

6.  Permeability-increasing activity in hereditary angioneurotic edema plasma. II. Mechanism of formation and partial characterization.

Authors:  V H Donaldson; O D Ratnoff; W Dias Da Silva; F S Rosen
Journal:  J Clin Invest       Date:  1969-04       Impact factor: 14.808

7.  A PROTEOLYTIC ENZYME OF SERUM: CHARACTERIZATION, ACTIVATION, AND REACTION WITH INHIBITORS.

Authors:  L R Christensen; C M Macleod
Journal:  J Gen Physiol       Date:  1945-07-20       Impact factor: 4.086

8.  Studies on a proteolytic enzyme in human plasma; the relationship between the proteolytic activity of plasma and blood coagulation.

Authors:  O D RATNOFF; R C HARTMANN; C L CONLEY
Journal:  J Exp Med       Date:  1950-02       Impact factor: 14.307

9.  Proteolytic enzymes; further studies on protein, polypeptide, and other inhibitors of serum proteinase, leucoproteinase, trypsin, and papain.

Authors:  D GROB
Journal:  J Gen Physiol       Date:  1949-11       Impact factor: 4.086

10.  Mechanisms of activation of C'1 esterase in hereditary angioneurotic edema plasma in vitro.

Authors:  V H Donaldson
Journal:  J Exp Med       Date:  1968-03-01       Impact factor: 14.307
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