Cholecystokinin Activity of Urine.

In the urine of men and animals was found a factor which evokes the contraction of the gall bladder. This factor increases in the urine after the application of a secretogenous stimulus to the duodenum and decreases after resection of the duodenum. A urine concentrate was prepared which has an effect similar to that of cholecystokinin administered intravenously and which was therefore called urocholecystokinin.