AIM: To evaluate whether the prevalence of overweight and obese conditions is increased in gastro-esophageal reflux disease (GERD) patients (with 24-h pathological pH recordings) in comparison to general population. METHODS: A total of 196 consecutive patients (103 females, age range 18-83 years) with symptoms of gastro-esophageal reflux (GER) and 24-h pathological esophageal pH-metry. Body mass index (BMI) of the patients was calculated and its distribution (%) was compared with that of the Italian general population as assessed by National Bureau of Census (ISTAT). To evaluate the association of GERD with weight categories, the binomial test was employed. P < 0.05 was considered statistically significant. RESULTS: In males, overweightedness (BMI 25-25.9) was present in 43% of GERD patients vs 41.8% of Italian population (IP) (ns), obesity (BMI > or = 30) in 10.9% vs 9.1% (ns). In females overweight was present in 34.9% of GERD patients vs 25.7% of IP (P < 0.01), obesity in 13.6% of GERD patients vs 9.1% of IP (P < 0.01). No statistically significant differences were noted in different age classes. CONCLUSION: In comparison to the Italian general population, the prevalence of overweightedness and obesity is increased in female but not in male patients with ascertained gastro-esophageal reflux disease.
AIM: To evaluate whether the prevalence of overweight and obese conditions is increased in gastro-esophageal reflux disease (GERD) patients (with 24-h pathological pH recordings) in comparison to general population. METHODS: A total of 196 consecutive patients (103 females, age range 18-83 years) with symptoms of gastro-esophageal reflux (GER) and 24-h pathological esophageal pH-metry. Body mass index (BMI) of the patients was calculated and its distribution (%) was compared with that of the Italian general population as assessed by National Bureau of Census (ISTAT). To evaluate the association of GERD with weight categories, the binomial test was employed. P < 0.05 was considered statistically significant. RESULTS: In males, overweightedness (BMI 25-25.9) was present in 43% of GERDpatients vs 41.8% of Italian population (IP) (ns), obesity (BMI > or = 30) in 10.9% vs 9.1% (ns). In females overweight was present in 34.9% of GERDpatients vs 25.7% of IP (P < 0.01), obesity in 13.6% of GERDpatients vs 9.1% of IP (P < 0.01). No statistically significant differences were noted in different age classes. CONCLUSION: In comparison to the Italian general population, the prevalence of overweightedness and obesity is increased in female but not in male patients with ascertained gastro-esophageal reflux disease.
Authors: Jean Paul Galmiche; Ray E Clouse; András Bálint; Ian J Cook; Peter J Kahrilas; William G Paterson; Andre J P M Smout Journal: Gastroenterology Date: 2006-04 Impact factor: 22.682
Authors: Fabian Springer; Manuel Schwarz; Jürgen Machann; Andreas Fritsche; Claus D Claussen; Fritz Schick; Joachim H Schneider Journal: Obes Surg Date: 2010-06 Impact factor: 4.129
Authors: Juliane M E Schneider; Björn L D M Brücher; Markus Küper; Kathrin Saemann; Alfred Königsrainer; Joachim H Schneider Journal: Obes Surg Date: 2008-07-22 Impact factor: 4.129