Literature DB >> 17729400

Distribution of solitary lymph nodes in primary gastric cancer: a retrospective study and clinical implications.

Cai-Gang Liu1, Ping Lu, Yang Lu, Feng Jin, Hui-Mian Xu, Shu-Bao Wang, Jun-Qing Chen.   

Abstract

AIM: To investigate the distribution pathway of metastatic lymph nodes in gastric carcinoma as a foundation for rational lymphadenectomy.
METHODS: We investigated 173 cases with solitary or single station metastatic lymph nodes (LN) from among 2476 gastric carcinoma patients. The location of metastatic LN, histological type and growth patterns were analyzed retrospectively.
RESULTS: Of 88 solitary node metastases cases, 65 were limited to perigastric nodes (N(1)), while 23 showed skipping metastasis. Among 8 tumors in the upper third stomach, 3 involved right paracardial LN (station number: No.1), and one in the greater curvature was found in No.1. In the 28 middle third stomach tumors, 10 were found in LN of the lesser curvature (No.3) and 6 in LN of the left gastric artery (No.7); 5 of the 20 cases on the lesser curvature spread to No.7, while 2 of the 8 on the greater curvature metastasized to LN of the spleen hilum (No.10). Of 52 lower third stomach tumors, 13 involved in No.3 and 19 were detected in inferior pyloric LN (No.6); 9 of the 29 cases along the lesser curvature were involved in No.6.
CONCLUSION: Transversal and skipping metastases of sentinel lymph nodes (SLN) are notable, and rational lymphadenectomy should, therefore, be performed.

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Mesh:

Year:  2007        PMID: 17729400      PMCID: PMC4611200          DOI: 10.3748/wjg.v13.i35.4776

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  21 in total

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Authors:  Yinzhong Wang
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7.  Characteristics and survival outcomes related to the infra-pyloric lymph node status of gastric cancer patients.

Authors:  Wei-Han Zhang; Xiao-Hai Song; Xin-Zu Chen; Kun Yang; Kai Liu; Zhi-Xin Chen; Zong-Guang Zhou; Jian-Kun Hu
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Authors:  Yang Lu; Ping Lu; Zhi Zhu; Huimian Xu; Xike Zhu
Journal:  J Exp Clin Cancer Res       Date:  2009-09-09
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