Literature DB >> 17728852

Beta-amino acid-containing hybrid peptides--new opportunities in peptidomimetics.

Marie-Isabel Aguilar1, Anthony W Purcell, Romila Devi, Rebecca Lew, Jamie Rossjohn, A Ian Smith, Patrick Perlmutter.   

Abstract

Hybrid peptides consisting of alpha-amino acids with judiciously placed beta-amino acids show great promise as peptidomimetics in an increasing range of therapeutic applications. This reflects a combination of increased stability, high specificity and relative ease of synthesis.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17728852     DOI： 10.1039/b708507a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  21 in total

Review 1.  Post-translationally modified T cell epitopes: immune recognition and immunotherapy.

Authors:  Jan Petersen; Anthony W Purcell; Jamie Rossjohn
Journal:  J Mol Med (Berl)       Date:  2009-09-08       Impact factor: 4.599

2.  Evaluation of β-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure.

Authors:  David E Mortenson; Dale F Kreitler; Nicole C Thomas; Ilia A Guzei; Samuel H Gellman; Katrina T Forest
Journal:  Chembiochem       Date:  2018-02-13       Impact factor: 3.164

3.  β-Aminopeptidases: Insight into Enzymes without a Known Natural Substrate.

Authors:  Marietta John-White; James Gardiner; Priscilla Johanesen; Dena Lyras; Geoffrey Dumsday
Journal:  Appl Environ Microbiol       Date:  2019-07-18       Impact factor: 4.792

4.  Enantioselective catalytic synthesis of α-aryl-α-SCF3-β2,2-amino acids.

Authors:  Andreas Eitzinger; Jean-François Brière; Dominique Cahard; Mario Waser
Journal:  Org Biomol Chem       Date:  2020-01-22       Impact factor: 3.876

5.  Effects of Single α-to-β Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.

Authors:  Dale F Kreitler; David E Mortenson; Katrina T Forest; Samuel H Gellman
Journal:  J Am Chem Soc       Date:  2016-05-12       Impact factor: 15.419

6.  Introducing D-amino acid or simple glycoside into small peptides to enable supramolecular hydrogelators to resist proteolysis.

Authors:  Xinming Li; Xuewen Du; Jiayang Li; Yuan Gao; Yue Pan; Junfeng Shi; Ning Zhou; Bing Xu
Journal:  Langmuir       Date:  2012-09-04       Impact factor: 3.882

7.  Synthesis of glycosylated β³-homo-threonine conjugates for mucin-like glycopeptide antigen analogues.

Authors:  Florian Karch; Anja Hoffmann-Röder
Journal:  Beilstein J Org Chem       Date:  2010-05-12       Impact factor: 2.883

8.  Vinylaluminum addition to sulfinimines (N-sulfinyl imines). Asymmetric synthesis of anti-alpha-alkyl beta-amino esters.

Authors:  Franklin A Davis; Hui Qiu; Minsoo Song; Narendra V Gaddiraju
Journal:  J Org Chem       Date:  2009-04-03       Impact factor: 4.354

9.  Investigation of the substrate specificity of lacticin 481 synthetase by using nonproteinogenic amino acids.

Authors:  Matthew R Levengood; Christopher C Kerwood; Champak Chatterjee; Wilfred A van der Donk
Journal:  Chembiochem       Date:  2009-03-23       Impact factor: 3.164

10.  Can alpha- and beta-alanine containing peptides be distinguished based on the CID spectra of their protonated ions?

Authors:  Adrian K Y Lam; Sri H Ramarathinam; Anthony W Purcell; Richard A J O'Hair
Journal:  J Am Soc Mass Spectrom       Date:  2008-09-12       Impact factor: 3.109
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.