Literature DB >> 17727977

Biochemical properties of an intracellular serpin from Echinococcus multilocularis.

Armin Merckelbach1, Andreas Ruppel.   

Abstract

A serpin of the intracellular type from the tapeworm Echinococcus multilocularis was expressed in Escherichia coli, purified by ion exchange chromatography and tested for inhibitory activity against several proteinases. The recombinant protein, which after transcriptional induction, represents about 20 % of total cellular protein, is biochemically active and inhibits trypsin and the trypsin-like plasmin as well as pig pancreatic and human neutrophil elastase. Implications regarding its biochemistry and biological function are discussed.

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Year:  2007        PMID： 17727977     DOI： 10.1016/j.molbiopara.2007.07.013

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


  7 in total

1.  The biochemical and immunological characterization of two serpins from Clonorchis sinensis.

Authors:  Huali Lei; Yanli Tian; Wenjun Chen; Xiaoyun Wang; Xuerong Li; Qiang Mao; Jiufeng Sun; Ran Li; Yanquan Xu; Chi Liang; Yan Huang; Xinbing Yu
Journal:  Mol Biol Rep       Date:  2012-12-30       Impact factor: 2.316

2.  Identification and characterization of a serine protease inhibitor of Paragonimus westermani.

Authors:  Jin-Hee Hwang; Wook-Gyo Lee; Byoung-Kuk Na; Hyeong-Woo Lee; Shin-Hyeong Cho; Tong-Soo Kim
Journal:  Parasitol Res       Date:  2008-10-17       Impact factor: 2.289

3.  Identification and characterization of the second cysteine protease inhibitor of Clonorchis sinensis (CsStefin-2).

Authors:  Jung-Mi Kang; Hye-Lim Ju; Kon Ho Lee; Tong-Soo Kim; Jhang Ho Pak; Woon-Mok Sohn; Byoung-Kuk Na
Journal:  Parasitol Res       Date:  2013-10-08       Impact factor: 2.289

4.  Characterisation of a secretory serine protease inhibitor (SjB6) from Schistosoma japonicum.

Authors:  Adebayo J Molehin; Geoffrey N Gobert; Patrick Driguez; Donald P McManus
Journal:  Parasit Vectors       Date:  2014-07-14       Impact factor: 3.876

5.  Identification and partial characterization of a novel serpin from Eudiplozoon nipponicum (Monogenea, Polyopisthocotylea).

Authors:  Pavel Roudnický; Jiří Vorel; Jana Ilgová; Michal Benovics; Adam Norek; Lucie Jedličková; Libor Mikeš; David Potěšil; Zbyněk Zdráhal; Jan Dvořák; Milan Gelnar; Martin Kašný
Journal:  Parasite       Date:  2018-12-05       Impact factor: 3.000

6.  Analysis on Gene Expression Profile in Oncospheres and Early Stage Metacestodes from Echinococcus multilocularis.

Authors:  Fuqiang Huang; Zhisheng Dang; Yutaka Suzuki; Terumi Horiuchi; Kinpei Yagi; Hirokazu Kouguchi; Takao Irie; Kyeongsoon Kim; Yuzaburo Oku
Journal:  PLoS Negl Trop Dis       Date:  2016-04-19

7.  Characterization of a serine protease inhibitor from Trichinella spiralis and its participation in larval invasion of host's intestinal epithelial cells.

Authors:  Yan Yan Song; Yao Zhang; Hua Nan Ren; Ge Ge Sun; Xin Qi; Fan Yang; Peng Jiang; Xi Zhang; Jing Cui; Zhong Quan Wang
Journal:  Parasit Vectors       Date:  2018-09-06       Impact factor: 3.876
  7 in total

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