Literature DB >> 17726596

[68-year-old female patient with dyspnea and hypokalemic hypertension].

K Müssig1, C Maser-Gluth, M Hartmann, M Wehrmann, M Horger, L Kanz, H-U Häring, S A Wudy.   

Abstract

Ectopic ACTH syndrome is a rare differential diagnosis of hypokalemic hypertension. Patients with ectopic ACTH syndrome due to small cell lung cancer have a poor prognosis. We report on a 68-year-old female patient who presented with dyspnea and hypokalemic hypertension. Endocrine testing was consistent with ectopic ACTH syndrome due to small cell lung cancer. After initiation of chemotherapy with etoposide and carboplatin ACTH and cortisol levels normalized and clinical symptoms impressively improved.

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Year:  2007        PMID： 17726596     DOI： 10.1007/s00108-007-1930-x

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN： 0020-9554            Impact factor:   0.743


  12 in total

Review 1.  11 beta-Hydroxysteroid dehydrogenase and enzyme-mediated receptor protection: life after liquorice?

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Journal:  Clin Endocrinol (Oxf)       Date:  1991-10       Impact factor: 3.478

Review 2.  The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states.

Authors:  J Newell-Price; P Trainer; M Besser; A Grossman
Journal:  Endocr Rev       Date:  1998-10       Impact factor: 19.871

3.  Mineralocorticoid specificity of renal type I receptors: in vivo binding studies.

Authors:  K Sheppard; J W Funder
Journal:  Am J Physiol       Date:  1987-02

4.  Ectopic ACTH syndrome. Diagnostic and therapeutic aspects.

Authors:  R K Jex; J A van Heerden; P C Carpenter; C S Grant
Journal:  Am J Surg       Date:  1985-02       Impact factor: 2.565

Review 5.  Ectopic ACTH syndrome: molecular bases and clinical heterogeneity.

Authors:  M Terzolo; G Reimondo; A Alì; S Bovio; F Daffara; P Paccotti; A Angeli
Journal:  Ann Oncol       Date:  2001       Impact factor: 32.976

Review 6.  Hypertension and the cortisol-cortisone shuttle.

Authors:  Marcus Quinkler; Paul M Stewart
Journal:  J Clin Endocrinol Metab       Date:  2003-06       Impact factor: 5.958

7.  Paraneoplastic Cushing's syndrome as an adverse prognostic factor in patients who die early with small cell lung cancer.

Authors:  M A Dimopoulos; J F Fernandez; N A Samaan; P Y Holoye; R Vassilopoulou-Sellin
Journal:  Cancer       Date:  1992-01-01       Impact factor: 6.860

8.  Cushing's syndrome associated with ectopic corticotropin production and small-cell lung cancer.

Authors:  F A Shepherd; J Laskey; W K Evans; P E Goss; E Johansen; F Khamsi
Journal:  J Clin Oncol       Date:  1992-01       Impact factor: 44.544

9.  11 beta-Hydroxysteroid dehydrogenase activity in Cushing's syndrome: explaining the mineralocorticoid excess state of the ectopic adrenocorticotropin syndrome.

Authors:  P M Stewart; B R Walker; G Holder; D O'Halloran; C H Shackleton
Journal:  J Clin Endocrinol Metab       Date:  1995-12       Impact factor: 5.958

Review 10.  Cushing's syndrome.

Authors:  D N Orth
Journal:  N Engl J Med       Date:  1995-03-23       Impact factor: 91.245
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