Literature DB >> 17724805

Diagnostic accuracy of a rapid fecal test to confirm H pylori eradication after therapy: prospective comparison with a laboratory stool test.

Lucio Trevisani1, Viviana Cifalà, Nadia Fusetti, Giuseppe Gilli, Paola Tombesi, Marco Torchiaro, Sergio Boccia, Vincenzo Abbasciano.   

Abstract

AIM: To investigate the clinical performances of rapid stool test (ImmunoCard STAT HpSA, Meridian Diagnostic Inc.) in the evaluation of eradication therapy of H pylori and to compare it with a well-known and validated laboratory stool test (Amplified IDEA Hp StAR, Dako).
METHODS: Stool samples of 122 patients were evaluated after eradication therapy of H pylori. H pylori status was assessed by 13C-urea breath test (UBT). Stool specimens were tested using either the rapid immunoassay kit or the laboratory immunoassay kit.
RESULTS: Forty-three patients were infected and 79 non-infected. Sensitivity and specificity of ImmunoCard STAT and Hp StAR were 58.14% and 76.4%, and 97.47% and 98.73%, respectively (P > 0.05). Overall agreement between the two tests was 92.6% (113 of 122 cases).
CONCLUSION: ImmunoCard STAT seems to have rather low performances, and it cannot be regarded as a reliable tool in the post-treatment setting. Also Hp StAR cannot be recommended to confirm H pylori eradication after treatment.

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Year:  2007        PMID: 17724805      PMCID: PMC4611582          DOI: 10.3748/wjg.v13.i33.4484

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  40 in total

1.  Evaluation of a new rapid lateral flow chromatography test for the diagnosis of Helicobacter pylori.

Authors:  Nese Kaklikkaya; Remzi A Akdogan; Orhan Ozgur; Dogan Y Uzun; Umit Cobanoglu; Ugur Dinc; Erdal Gungor; Pinar A Dabanca; Mehmet Arslan; Faruk Aydin; Murat Erturk
Journal:  Saudi Med J       Date:  2006-06       Impact factor: 1.484

2.  Evaluation of a new rapid immunoassay for the detection of Helicobacter pylori in faeces: a prospective pilot study.

Authors:  L Trevisani; S Sartori; M R Rossi; M Ruina; V Matarese; S Gullini; V Abbasciano
Journal:  Aliment Pharmacol Ther       Date:  2005-02-15       Impact factor: 8.171

3.  Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report.

Authors:  P Malfertheiner; F Megraud; C O'Morain; F Bazzoli; E El-Omar; D Graham; R Hunt; T Rokkas; N Vakil; E J Kuipers
Journal:  Gut       Date:  2006-12-14       Impact factor: 23.059

4.  Comparison of a monoclonal with a polyclonal antibody-based enzyme immunoassay stool test in diagnosing Helicobacter pylori infection before and after eradication therapy.

Authors:  J Domínguez; M Forné; S Blanco; C Prat; N Galí; I Latorre; J M Viver; V Ausina
Journal:  Aliment Pharmacol Ther       Date:  2006-06-15       Impact factor: 8.171

5.  The accuracy of the Helicobacter pylori stool antigen test in diagnosing H. pylori in treated patients.

Authors:  L Trevisani; S Sartori
Journal:  Eur J Gastroenterol Hepatol       Date:  2002-01       Impact factor: 2.566

6.  [The diagnostic validity of Helicobacter pylori stool antigen test in the pre- and post-eradication].

Authors:  Ki Tae Kwon; Dong Seok Lee; In Kwon Chung; Min Jae Park; Chang Keun Park; Chang Min Cho; Won Young Tak; Young Oh Kweon; Sung Kook Kim; Yong Hwan Choi
Journal:  Korean J Gastroenterol       Date:  2004-10

7.  The accuracy of the Helicobacter pylori stool antigen test in diagnosing H. pylori in treated and untreated patients.

Authors:  N L Arents; A A van Zwet; J C Thijs; A de Jong; M O Pool; J H Kleibeuker
Journal:  Eur J Gastroenterol Hepatol       Date:  2001-04       Impact factor: 2.566

Review 8.  Stool antigen test for the diagnosis of Helicobacter pylori infection: a systematic review.

Authors:  Javier P Gisbert; José María Pajares
Journal:  Helicobacter       Date:  2004-08       Impact factor: 5.753

9.  Eradication of Helicobacter pylori reduces the possibility of rebleeding in peptic ulcer disease.

Authors:  T Rokkas; A Karameris; A Mavrogeorgis; E Rallis; N Giannikos
Journal:  Gastrointest Endosc       Date:  1995-01       Impact factor: 9.427

10.  Multiple-step polyclonal versus one-step monoclonal enzyme immunoassay in the detection of Helicobacter pylori antigen in the stools of children.

Authors:  Bruno Hauser; Inge Wybo; Gerard Tshibuabua; Dennis Pierard; Yvan Vandenplas
Journal:  Acta Paediatr       Date:  2006-03       Impact factor: 2.299

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