Literature DB >> 17723211

Islet beta-cell death - fuel to sustain autoimmunity?

Christophe M Filippi1, Matthias G von Herrath.   

Abstract

Under what context do dying beta-cells enhance the autoimmune process in type 1 diabetes? Kim et al. (2007) find that secondary necrosis of beta-cells can prime the autoimmune response via uptake by and activation of antigen-presenting cells through Toll-like receptor 2.

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Year:  2007        PMID： 17723211     DOI： 10.1016/j.immuni.2007.08.002

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  8 in total

1.  Infusion of UVB-treated splenic stromal cells induces suppression of beta cell antigen-specific T cell responses in NOD mice.

Authors:  Chang-Qing Xia; Yushi Qiu; Rui-Hua Peng; Jeannette Lo-Dauer; Michael J Clare-Salzler
Journal:  J Autoimmun       Date:  2008-01-15       Impact factor: 7.094

2.  TLR2 signaling improves immunoregulation to prevent type 1 diabetes.

Authors:  Christophe M Filippi; Katrin Ehrhardt; Elizabeth A Estes; Par Larsson; Janine E Oldham; Matthias G von Herrath
Journal:  Eur J Immunol       Date:  2011-05       Impact factor: 5.532

Review 3.  The role of inflammation in insulitis and beta-cell loss in type 1 diabetes.

Authors:  Décio L Eizirik; Maikel L Colli; Fernanda Ortis
Journal:  Nat Rev Endocrinol       Date:  2009-04       Impact factor: 43.330

Review 4.  The potential of targeting Toll-like receptor 2 in autoimmune and inflammatory diseases.

Authors:  E M Pålsson-McDermott; L A J O'Neill
Journal:  Ir J Med Sci       Date:  2007-11-15       Impact factor: 1.568

5.  α1-antitrypsin increases interleukin-1 receptor antagonist production during pancreatic islet graft transplantation.

Authors:  Avishag Abecassis; Ronen Schuster; Galit Shahaf; Eyal Ozeri; Ross Green; David E Ochayon; Peleg Rider; Eli C Lewis
Journal:  Cell Mol Immunol       Date:  2014-04-07       Impact factor: 11.530

6.  PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis.

Authors:  Fabrice Moore; Maikel L Colli; Miriam Cnop; Mariana Igoillo Esteve; Alessandra K Cardozo; Daniel A Cunha; Marco Bugliani; Piero Marchetti; Décio L Eizirik
Journal:  Diabetes       Date:  2009-03-31       Impact factor: 9.461

7.  Viral trigger for type 1 diabetes: pros and cons.

Authors:  Christophe M Filippi; Matthias G von Herrath
Journal:  Diabetes       Date:  2008-11       Impact factor: 9.461

Review 8.  The Role of Interleukin-1β in Destruction of Transplanted Islets.

Authors:  Cheng Chen; Pengfei Rong; Min Yang; Xiaoqian Ma; Zhichao Feng; Wei Wang
Journal:  Cell Transplant       Date:  2020 Jan-Dec       Impact factor: 4.064
  8 in total

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