Literature DB >> 17723208

Revving the engine: signal transduction fuels T cell activation.

Russell G Jones1, Craig B Thompson.   

Abstract

For initiation of an immune response, resting T cells must reprogram their metabolism. Continuing the "From the Field" series (see Editorial [2007] 26, 131), Jones and Thompson draw attention to the importance of metabolism during T cell activation and consider how this process is regulated by receptor-mediated signal transduction.

Mesh:

Year:  2007        PMID: 17723208     DOI: 10.1016/j.immuni.2007.07.008

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  171 in total

1.  The liver kinase B1 is a central regulator of T cell development, activation, and metabolism.

Authors:  Nancie J MacIver; Julianna Blagih; Donte C Saucillo; Luciana Tonelli; Takla Griss; Jeffrey C Rathmell; Russell G Jones
Journal:  J Immunol       Date:  2011-09-19       Impact factor: 5.422

2.  Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease.

Authors:  Erin Gatza; Daniel R Wahl; Anthony W Opipari; Thomas B Sundberg; Pavan Reddy; Chen Liu; Gary D Glick; James L M Ferrara
Journal:  Sci Transl Med       Date:  2011-01-26       Impact factor: 17.956

Review 3.  Staying alive: metabolic adaptations to quiescence.

Authors:  James R Valcourt; Johanna M S Lemons; Erin M Haley; Mina Kojima; Olukunle O Demuren; Hilary A Coller
Journal:  Cell Cycle       Date:  2012-05-01       Impact factor: 4.534

4.  Differential dependence on cysteine from transsulfuration versus transport during T cell activation.

Authors:  Sanjay K Garg; Zhonghua Yan; Victor Vitvitsky; Ruma Banerjee
Journal:  Antioxid Redox Signal       Date:  2010-12-02       Impact factor: 8.401

5.  Pharmacologic induction of CD8+ T cell memory: better living through chemistry.

Authors:  Luca Gattinoni; Christopher A Klebanoff; Nicholas P Restifo
Journal:  Sci Transl Med       Date:  2009-12-16       Impact factor: 17.956

Review 6.  Early events governing memory CD8+ T-cell differentiation.

Authors:  Joshua J Obar; Leo Lefrançois
Journal:  Int Immunol       Date:  2010-05-26       Impact factor: 4.823

7.  Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus.

Authors:  Hiroshi Kato; Andras Perl
Journal:  J Immunol       Date:  2014-03-28       Impact factor: 5.422

Review 8.  The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism.

Authors:  Jonathan D Powell; Greg M Delgoffe
Journal:  Immunity       Date:  2010-09-24       Impact factor: 31.745

9.  Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation.

Authors:  Hung D Nguyen; Shilpak Chatterjee; Kelley M K Haarberg; Yongxia Wu; David Bastian; Jessica Heinrichs; Jianing Fu; Anusara Daenthanasanmak; Steven Schutt; Sharad Shrestha; Chen Liu; Honglin Wang; Hongbo Chi; Shikhar Mehrotra; Xue-Zhong Yu
Journal:  J Clin Invest       Date:  2016-03-07       Impact factor: 14.808

10.  Effector T cells require fatty acid metabolism during murine graft-versus-host disease.

Authors:  Craig A Byersdorfer; Victor Tkachev; Anthony W Opipari; Stefanie Goodell; Jacob Swanson; Stacy Sandquist; Gary D Glick; James L M Ferrara
Journal:  Blood       Date:  2013-09-17       Impact factor: 22.113

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