Literature DB >> 17722920

A single-point mutation converts the highly amyloidogenic human islet amyloid polypeptide into a potent fibrillization inhibitor.

Andisheh Abedini1, Fanling Meng, Daniel P Raleigh.   

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Year:  2007        PMID： 17722920     DOI： 10.1021/ja072157y

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


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  74 in total

1.  The sulfated triphenyl methane derivative acid fuchsin is a potent inhibitor of amyloid formation by human islet amyloid polypeptide and protects against the toxic effects of amyloid formation.

Authors:  Fanling Meng; Andisheh Abedini; Annette Plesner; Chris T Middleton; Kathryn J Potter; Martin T Zanni; C Bruce Verchere; Daniel P Raleigh
Journal:  J Mol Biol       Date:  2010-05-07       Impact factor: 5.469

2.  Analysis of the inhibition and remodeling of islet amyloid polypeptide amyloid fibers by flavanols.

Authors:  Ping Cao; Daniel P Raleigh
Journal:  Biochemistry       Date:  2012-03-21       Impact factor: 3.162

3.  A variational model for oligomer-formation process of GNNQQNY peptide from yeast prion protein Sup35.

Authors:  Xianghong Qi; Liu Hong; Yang Zhang
Journal:  Biophys J       Date:  2012-02-07       Impact factor: 4.033

4.  Converting the highly amyloidogenic human calcitonin into a powerful fibril inhibitor by three-dimensional structure homology with a non-amyloidogenic analogue.

Authors:  Giuseppina Andreotti; Rosa Maria Vitale; Carmit Avidan-Shpalter; Pietro Amodeo; Ehud Gazit; Andrea Motta
Journal:  J Biol Chem       Date:  2010-11-15       Impact factor: 5.157

5.  Inhibition of glycosaminoglycan-mediated amyloid formation by islet amyloid polypeptide and proIAPP processing intermediates.

Authors:  Fanling Meng; Daniel P Raleigh
Journal:  J Mol Biol       Date:  2010-12-30       Impact factor: 5.469

6.  Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells.

Authors:  Praveen Nedumpully-Govindan; Esteban N Gurzov; Pengyu Chen; Emily H Pilkington; William J Stanley; Sara A Litwak; Thomas P Davis; Pu Chun Ke; Feng Ding
Journal:  Phys Chem Chem Phys       Date:  2015-12-02       Impact factor: 3.676

Review 7.  Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity.

Authors:  Ping Cao; Peter Marek; Harris Noor; Vadim Patsalo; Ling-Hsien Tu; Hui Wang; Andisheh Abedini; Daniel P Raleigh
Journal:  FEBS Lett       Date:  2013-02-01       Impact factor: 4.124

8.  Mechanism of IAPP amyloid fibril formation involves an intermediate with a transient β-sheet.

Authors:  Lauren E Buchanan; Emily B Dunkelberger; Huong Q Tran; Pin-Nan Cheng; Chi-Cheng Chiu; Ping Cao; Daniel P Raleigh; Juan J de Pablo; James S Nowick; Martin T Zanni
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-11       Impact factor: 11.205

9.  Cyclic N-terminal loop of amylin forms non amyloid fibers.

Authors:  Stephanie M Cope; Sandip Shinde; Robert B Best; Giovanna Ghirlanda; Sara M Vaiana
Journal:  Biophys J       Date:  2013-10-01       Impact factor: 4.033

10.  A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes.

Authors:  James A Hebda; Ishu Saraogi; Mazin Magzoub; Andrew D Hamilton; Andrew D Miranker
Journal:  Chem Biol       Date:  2009-09-25
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