| Literature DB >> 17721107 |
Padmini Srikantiah1, Maria N Walusimbi, H Kose Kayanja, Harriet Mayanja-Kizza, Roy D Mugerwa, Royce Lin, Edwin D Charlebois, W Henry Boom, Christopher C Whalen, Diane V Havlir.
Abstract
Triple nucleoside reverse transcriptase inhibitors are recommended as an alternative regimen for HIV-infected patients undergoing tuberculosis treatment in resource-limited settings. Few data exist on the efficacy of such regimens in tuberculosis patients. In 34 tuberculosis/HIV-co-infected patients treated with zidovudine/lamivudine/abacavir, 76% achieved HIV RNA less than 50 copies/ml at 24 weeks. No cases of hypersensitivity or immune reconstitution syndrome were observed. These data support the continuing evaluation of nucleoside-based antiretroviral regimens as an alternative treatment for this population.Entities:
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Year: 2007 PMID: 17721107 PMCID: PMC4752198 DOI: 10.1097/QAD.0b013e32823ecf6e
Source DB: PubMed Journal: AIDS ISSN: 0269-9370 Impact factor: 4.177