BACKGROUND AND PURPOSE: To assess safety and efficacy data of a new bioactive coil (Cerecyte) which is loaded with polyglycolic acid on the inside of the coil. METHODS: Fifty-four patients harboring 55 aneurysms were treated with Cerecyte coils. These aneurysms were matched in localization and size with aneurysms treated with bare platinum coils. RESULTS: Periprocedural complications and handling did not differ between both groups. Initial aneurysm occlusion was comparable in both treatment groups. At 6 months angiographic follow-up, the aneurysms occluded with Cerecyte coils had a higher chance for complete occlusion (P=0.045) and tended to a lower retreatment rate (P=0.056). CONCLUSIONS: Cerecyte coils are as safe as bare platinum coils in the endovascular occlusion of aneurysms. This matched pair analysis indicates a higher occlusion rate of aneurysms occluded with Cerecyte coils.
BACKGROUND AND PURPOSE: To assess safety and efficacy data of a new bioactive coil (Cerecyte) which is loaded with polyglycolic acid on the inside of the coil. METHODS: Fifty-four patients harboring 55 aneurysms were treated with Cerecyte coils. These aneurysms were matched in localization and size with aneurysms treated with bare platinum coils. RESULTS: Periprocedural complications and handling did not differ between both groups. Initial aneurysm occlusion was comparable in both treatment groups. At 6 months angiographic follow-up, the aneurysms occluded with Cerecyte coils had a higher chance for complete occlusion (P=0.045) and tended to a lower retreatment rate (P=0.056). CONCLUSIONS: Cerecyte coils are as safe as bare platinum coils in the endovascular occlusion of aneurysms. This matched pair analysis indicates a higher occlusion rate of aneurysms occluded with Cerecyte coils.
Authors: S Coley; M Sneade; A Clarke; Z Mehta; D Kallmes; S Cekirge; I Saatci; D Roy; A Molyneux Journal: AJNR Am J Neuroradiol Date: 2011-12-29 Impact factor: 3.825
Authors: Bradley A Gross; Ziad A Hage; Marc Daou; Christopher C Getch; H Hunt Batjer; Bernard R Bendok Journal: Curr Treat Options Cardiovasc Med Date: 2008-06