| Literature DB >> 17716893 |
Claudia Mugnaini1, Suvi Rajamaki, Cristina Tintori, Federico Corelli, Silvio Massa, Myriam Witvrouw, Zeger Debyser, Veljko Veljkovic, Maurizio Botta.
Abstract
The identification of a novel hit compound as integrase binding inhibitor has been accomplished by means of virtual screening techniques. A small family of structurally related molecules has been synthesized and biologically evaluated with one of the compounds showing an IC(50)=12 microM.Entities:
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Year: 2007 PMID： 17716893 DOI： 10.1016/j.bmcl.2007.08.005
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823