| Literature DB >> 17716883 |
Daniel N Streblow1, Susan L Orloff, Jay A Nelson.
Abstract
A number of human herpesviruses are important opportunistic pathogens that have been associated with increased morbidity and mortality in transplant recipients including human cytomegalovirus (HCMV), HHV6, HHV7, HHV8 as well as HSV-1, VZV. However, HCMV has been linked both epidemiologically and through the use of animal models to the acceleration of acute and chronic allograft rejection. This review will cover the pathophysiology, epidemiology, and mechanisms of CMV-associated disease in the setting of transplantation.Entities:
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Year: 2007 PMID: 17716883 PMCID: PMC3509935 DOI: 10.1016/j.coi.2007.07.012
Source DB: PubMed Journal: Curr Opin Immunol ISSN: 0952-7915 Impact factor: 7.486