| Literature DB >> 17716777 |
Bernard Bruguerolle1, Gaston Labrecque.
Abstract
Pain control is one of the most important therapeutic priorities; nonetheless, inadequate pain relief remains a significant health care issue. Thus, it is important to determine whether the analgesic effect can be improved by using the chronopharmacological approach. This paper reviews the data on the rhythmic patterns in pain level and their chronotherapy. It underlines the major issues and problems related to the development of chronotherapeutic strategies, and it examines emerging aspects of new drug-delivery systems for achieving such.Entities:
Mesh:
Substances:
Year: 2007 PMID: 17716777 DOI: 10.1016/j.addr.2006.06.001
Source DB: PubMed Journal: Adv Drug Deliv Rev ISSN: 0169-409X Impact factor: 15.470