Literature DB >> 17715365

Make it or take it: fatty acid metabolism of apicomplexan parasites.

Jolly Mazumdar1, Boris Striepen.   

Abstract

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Year:  2007        PMID： 17715365      PMCID： PMC2043401          DOI： 10.1128/EC.00255-07

Source DB:  PubMed          Journal:  Eukaryot Cell        ISSN： 1535-9786


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  83 in total

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Review 2.  The biosynthesis of polyketide metabolites by dinoflagellates.

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Review 4.  Contribution of host lipids to Toxoplasma pathogenesis.

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5.  Crystal structure of dimeric FabZ of Plasmodium falciparum reveals conformational switching to active hexamers by peptide flips.

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Journal:  FEBS Lett       Date:  2006-04-21       Impact factor: 4.124

Review 6.  Metabolic maps and functions of the Plasmodium mitochondrion.

Authors:  Giel G van Dooren; Luciana M Stimmler; Geoffrey I McFadden
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7.  Toxoplasma gondii acyl-lipid metabolism: de novo synthesis from apicoplast-generated fatty acids versus scavenging of host cell precursors.

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9.  Kinetic, inhibition and structural studies on 3-oxoacyl-ACP reductase from Plasmodium falciparum, a key enzyme in fatty acid biosynthesis.

Authors:  Sasala R Wickramasinghe; Kirstine A Inglis; Jonathan E Urch; Sylke Müller; Daan M F van Aalten; Alan H Fairlamb
Journal:  Biochem J       Date:  2006-01-15       Impact factor: 3.857

10.  Recombinant expression and biochemical characterization of the unique elongating beta-ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using natural and artificial substrates.

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  45 in total

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2.  Host cell autophagy is induced by Toxoplasma gondii and contributes to parasite growth.

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Journal:  J Biol Chem       Date:  2008-11-21       Impact factor: 5.157

3.  Crystal structure of the Mp1p ligand binding domain 2 reveals its function as a fatty acid-binding protein.

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Journal:  J Biol Chem       Date:  2010-01-06       Impact factor: 5.157

4.  Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites.

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5.  The import and export business in plastids: transport processes across the inner envelope membrane.

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6.  Factors mediating plastid dependency and the origins of parasitism in apicomplexans and their close relatives.

Authors:  Jan Janouškovec; Denis V Tikhonenkov; Fabien Burki; Alexis T Howe; Martin Kolísko; Alexander P Mylnikov; Patrick J Keeling
Journal:  Proc Natl Acad Sci U S A       Date:  2015-02-25       Impact factor: 11.205

7.  Novel Approaches To Kill Toxoplasma gondii by Exploiting the Uncontrolled Uptake of Unsaturated Fatty Acids and Vulnerability to Lipid Storage Inhibition of the Parasite.

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8.  Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs.

Authors:  Nadia Saïdani; Cyrille Y Botté; Michael Deligny; Anne-Laure Bonneau; Janette Reader; Ronald Lasselin; Goulven Merer; Alisson Niepceron; Fabien Brossier; Jean-Christophe Cintrat; Bernard Rousseau; Lyn-Marie Birkholtz; Marie-France Cesbron-Delauw; Jean-François Dubremetz; Corinne Mercier; Henri Vial; Roman Lopez; Eric Maréchal
Journal:  Antimicrob Agents Chemother       Date:  2014-02-18       Impact factor: 5.191

9.  The reductase domain in a Type I fatty acid synthase from the apicomplexan Cryptosporidium parvum: restricted substrate preference towards very long chain fatty acyl thioesters.

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Journal:  BMC Biochem       Date:  2010-11-22       Impact factor: 4.059

10.  Oleic acid biosynthesis in Plasmodium falciparum: characterization of the stearoyl-CoA desaturase and investigation as a potential therapeutic target.

Authors:  Paul Gratraud; Enlli Huws; Brie Falkard; Sophie Adjalley; David A Fidock; Laurence Berry; William R Jacobs; Mark S Baird; Henri Vial; Laurent Kremer
Journal:  PLoS One       Date:  2009-09-03       Impact factor: 3.240
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