Literature DB >> 177153

Osteoclast ultrastructure in Paget's disease.

A Rebel, K Malkani, M Baslé, C Bregeon.   

Abstract

The ultrastructural study of osteoclasts in biopsies from 12 patients with Paget's disease reveals several cytological anomalies. In Particular, nuclear inclusions, consisting essentially of striated filaments about 150 A in diameter, often organized in bundles and sometimes in paracrystalline arrays, appear to be specific to the disease. Morphologically, the inclusions are remarkably similar to those observed in various cases of viral attack, and the hypothesis of the action of a possible external agent in Paget's disease cannot be ruled out.

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Year:  1976        PMID： 177153     DOI： 10.1007/bf02546407

Source DB:  PubMed          Journal:  Calcif Tissue Res        ISSN： 0008-0594


  16 in total

1.  Endothelial inclusions and "nuclear bodies" in systemic lupus erythematosus.

Authors:  E O Dreyer; P Y Muldiyarov; V A Nassonova; Z S Alekberova
Journal:  Ann Rheum Dis       Date:  1973-09       Impact factor: 19.103

2.  Cytoplasmic vacuoles and bodies of the osteoclast. An electron microscope study.

Authors:  U Lucht
Journal:  Z Zellforsch Mikrosk Anat       Date:  1972

3.  Developmental pathway of granular and beaded nuclear bodies from nucleoli.

Authors:  A M Dupuy-Coin; M Bouteille
Journal:  J Ultrastruct Res       Date:  1972-07

Review 4.  Viruslike structures in systemic lupus erythematosus.

Authors:  G A Andres; H Spiele; R T McCluskey
Journal:  Prog Clin Immunol       Date:  1972

5.  Evidence of coated membranes in the ruffled border of the osteoclast.

Authors:  D M Kallio; P R Garant; C Minkin
Journal:  J Ultrastruct Res       Date:  1971-10

6.  Ultrastructural variations of nuclear bodies in human diseases.

Authors:  M Bouteille; S R Kalifat; J Delarue
Journal:  J Ultrastruct Res       Date:  1967-08-30

7.  Subacute sclerosing panencephalitis virus. Observations on a neuroadapted and non-neuroadapted strain in organotypic central nervous system cultures.

Authors:  C S Raine; L A Feldman; R D Sheppard; L H Barbosa; M B Bornstein
Journal:  Lab Invest       Date:  1974-07       Impact factor: 5.662

8.  [Nuclear anomalies in osteoclasts in Paget's bone disease].

Authors:  A Rebel; K Malkani; M Basle
Journal:  Nouv Presse Med       Date:  1974-05-18

9.  Cytoplasmic modifications at the contact zone of osteoclasts and calcified tissue in the diaphyseal growing plate of foetal guinea-pig tibia.

Authors:  K Malkani; M M Luxembourger; A Rebel
Journal:  Calcif Tissue Res       Date:  1973-03-12

10.  Electron microscopy of osteoclasts in healing fracturees of rat bone.

Authors:  F GONZALES; M J KARNOVSKY
Journal:  J Biophys Biochem Cytol       Date:  1961-02
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  19 in total

1.  Genetic linkage of Paget disease of the bone to chromosome 18q.

Authors:  J D Cody; F R Singer; G D Roodman; B Otterund; T B Lewis; M Leppert; R J Leach
Journal:  Am J Hum Genet       Date:  1997-11       Impact factor: 11.025

2.  Interleukin 6. A potential autocrine/paracrine factor in Paget's disease of bone.

Authors:  G D Roodman; N Kurihara; Y Ohsaki; A Kukita; D Hosking; A Demulder; J F Smith; F R Singer
Journal:  J Clin Invest       Date:  1992-01       Impact factor: 14.808

3.  Paget's disease of bone.

Authors: 
Journal:  Br Med J       Date:  1977-06-04

4.  Osteoclast-derived IGF1 is required for pagetic lesion formation in vivo.

Authors:  Kazuaki Miyagawa; Yasuhisa Ohata; Jesus Delgado-Calle; Jumpei Teramachi; Hua Zhou; David D Dempster; Mark A Subler; Jolene J Windle; John M Chirgwin; G David Roodman; Noriyoshi Kurihara
Journal:  JCI Insight       Date:  2020-03-26

5.  Atypical multinucleated cells form in long-term marrow cultures from patients with Paget's disease.

Authors:  A Kukita; C Chenu; L M McManus; G R Mundy; G D Roodman
Journal:  J Clin Invest       Date:  1990-04       Impact factor: 14.808

6.  The pathophysiology of bone and joint disease.

Authors:  S L Teitelbaum; P G Bullough
Journal:  Am J Pathol       Date:  1979-07       Impact factor: 4.307

7.  The treatment of metabolic bone disease.

Authors:  S Posen; P Clifton-Bligh; R S Mason
Journal:  Drugs       Date:  1979-04       Impact factor: 9.546

Review 8.  Viral aetiology of Paget's disease of bone: a review.

Authors:  L Harvey
Journal:  J R Soc Med       Date:  1984-11       Impact factor: 5.344

9.  Treatment of Paget's disease of bone with (4-chloro-phenyl) thiomethylene bisphosphonate.

Authors:  M Audran; P Clochon; D Etghen; B Mazieres; J C Renier
Journal:  Clin Rheumatol       Date:  1989-03       Impact factor: 2.980

10.  Effect of calcitonin treatment on osteoclast counts in Paget's disease of bone.

Authors:  C P Williams; G Meachim; W H Taylor
Journal:  J Clin Pathol       Date:  1978-12       Impact factor: 3.411
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