Literature DB >> 17713426

Understanding FOXP3: progress towards achieving transplantation tolerance.

Elaine Long1, Kathryn J Wood.   

Abstract

Regulatory T cells (Treg) suppress immune responses, making them an exciting therapeutic target for achieving operational transplant tolerance. Recent observations have identified forkhead box P3 (FOXP3) as a master gene required for the development and function of Treg. Improving our understanding of FOXP3 may facilitate methods for identifying and generating Treg.

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Year:  2007        PMID: 17713426     DOI: 10.1097/01.tp.0000275424.52998.ad

Source DB:  PubMed          Journal:  Transplantation        ISSN: 0041-1337            Impact factor:   4.939


  8 in total

Review 1.  Novel immune regulatory pathways and their role in immune reconstitution syndrome in organ transplant recipients with invasive mycoses.

Authors:  N Singh
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2008-01-23       Impact factor: 3.267

2.  Induction of antigen-specific immune tolerance by TGF-beta-induced CD4+Foxp3+ regulatory T cells.

Authors:  Huimin Fan; Julie Wang; Xiaohui Zhou; Zhongmin Liu; Song Guo Zheng
Journal:  Int J Clin Exp Med       Date:  2009-08-25

Review 3.  Physiopathology of idiopathic nephrotic syndrome: lessons from glucocorticoids and epigenetic perspectives.

Authors:  Valéry Elie; May Fakhoury; Georges Deschênes; Evelyne Jacqz-Aigrain
Journal:  Pediatr Nephrol       Date:  2011-06-28       Impact factor: 3.714

4.  Transforming growth factor beta 1 plays an important role in inducing CD4(+)CD25(+)forhead box P3(+) regulatory T cells by mast cells.

Authors:  W Zhang; K Wu; W He; Y Gao; W Huang; X Lin; L Cai; Z Fang; Q Zhou; Z Luo; Z K Chen; H Zhou
Journal:  Clin Exp Immunol       Date:  2010-09       Impact factor: 4.330

5.  Selective expression of latency-associated peptide (LAP) and IL-1 receptor type I/II (CD121a/CD121b) on activated human FOXP3+ regulatory T cells allows for their purification from expansion cultures.

Authors:  Dat Q Tran; John Andersson; Donna Hardwick; Lolita Bebris; Gabor G Illei; Ethan M Shevach
Journal:  Blood       Date:  2009-03-18       Impact factor: 22.113

6.  IL-12R beta 2 promotes the development of CD4+CD25+ regulatory T cells.

Authors:  Zhao Zhao; Shuo Yu; Denise C Fitzgerald; Mohamed Elbehi; Bogoljub Ciric; A M Rostami; Guang-Xian Zhang
Journal:  J Immunol       Date:  2008-09-15       Impact factor: 5.422

Review 7.  Tolerance-inducing immunosuppressive strategies in clinical transplantation: an overview.

Authors:  Dela Golshayan; Manuel Pascual
Journal:  Drugs       Date:  2008       Impact factor: 9.546

8.  Foxp3-modified bone marrow mesenchymal stem cells promotes liver allograft tolerance through the generation of regulatory T cells in rats.

Authors:  Haizhi Qi; Guangshun Chen; Yaxun Huang; Zhongzhou Si; Jiequn Li
Journal:  J Transl Med       Date:  2015-08-21       Impact factor: 5.531

  8 in total

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