Literature DB >> 17713273

[Application of fibrin glue in facial nerve repair].

Qinying Wang1, Qingquan Hua, Shenqing Wang.   

Abstract

This animal experiment was aimed to apply fibrin in facial nerve repair and to quest for technical improvements in facial surgery. In each of 15 healthy large ear white rabbits, a unilateral 5 mm intratemporal facial nerve gap was created, the proximal and distal stumps were inserted into chitin tube, 1 ml autologous fibrin glue was applied around the anastomotic zone, and no suture was employed. At 3 months and 5 months after opertion, electrophysioligical study was performed. Compared with normal nerves, the regenerating nerves in both the chitin tube bridged group and the perineurium suture group had longer incubation period, lower amplitude, slower nerve-muscle conduction velocity at 3 months postoperatively. The differences were distinctly significant (P < 0.01). Although being decreased at 5 months after operation, the differences were still statistically significant (P < 0.05). There were no significant differences between the chitin tube bridged group and perineurium suture group at 3 months and 5 months, respectively. The study suggests that facial nerve repair using fibrin glue and chitin tube has the advantages of being easier,faster and more stable.

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Year:  2007        PMID: 17713273

Source DB:  PubMed          Journal:  Sheng Wu Yi Xue Gong Cheng Xue Za Zhi        ISSN: 1001-5515


  2 in total

1.  Effects of primary suture and fibrin sealant on hemostasis and liver regeneration in an experimental liver injury.

Authors:  Arif Hakan Demirel; Ozgur Taylan Basar; Ali Ulvi Ongoren; Erkut Bayram; Mustafa Kisakurek
Journal:  World J Gastroenterol       Date:  2008-01-07       Impact factor: 5.742

2.  Impact of fetal brain tissue derived mesenchymal stem cell and fibrin glue on facial nerve crash injury

Authors:  Ömer Bayır; Tuğba Karagöz; Ferda Alpaslan Pınarlı; Gülistan Sanem Sarıbaş; Candan Özoğul; Kemal Keseroğlu; Güleser Saylam; Emel Çadallı Tatar; Sevilay Karahan; Bülent Öcal; Mehmet Hakan Korkmaz
Journal:  Turk J Med Sci       Date:  2021-06-28       Impact factor: 0.973

  2 in total

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