Literature DB >> 17709118

A stochastic model of immune-modulated malaria infection and disease in children.

David Gurarie1, F Ellis McKenzie.   

Abstract

We develop a simple three-state stochastic description of individual malaria infections that relates dynamics of disease and immune status to age and previous exposure, under different intensities of transmission. We apply the resulting individual-based community models to examine the effects of drug treatment and vaccination on the frequency and severity of disease in ensembles of children. The several broad qualitative similarities between our results and field observations include potential rebound effects following intervals of drug treatment.

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Year:  2007        PMID： 17709118      PMCID： PMC2173879          DOI： 10.1016/j.mbs.2007.07.001

Source DB:  PubMed          Journal:  Math Biosci        ISSN： 0025-5564            Impact factor:   2.144


  27 in total

1.  Severe malaria in children in areas with low, moderate and high transmission intensity in Uganda.

Authors:  R Idro; J Aloyo; L Mayende; E Bitarakwate; C C John; G W Kivumbi
Journal:  Trop Med Int Health       Date:  2006-01       Impact factor: 2.622

Review 2.  The clinical and pathophysiological features of malarial anaemia.

Authors:  D J Roberts; C Casals-Pascual; D J Weatherall
Journal:  Curr Top Microbiol Immunol       Date:  2005       Impact factor: 4.291

Review 3.  Clinical immunity to malaria.

Authors:  Louis Schofield; Ivo Mueller
Journal:  Curr Mol Med       Date:  2006-03       Impact factor: 2.222

4.  SEASONALITY, PARASITE DIVERSITY, AND LOCAL EXTINCTIONS IN PLASMODIUM FALCIPARUM MALARIA.

Authors:  F Ellis McKenzie; Gerry F Killeen; John C Beier; William H Bossert
Journal:  Ecology       Date:  2001       Impact factor: 5.499

5.  Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa.

Authors:  R W Snow; J A Omumbo; B Lowe; C S Molyneux; J O Obiero; A Palmer; M W Weber; M Pinder; B Nahlen; C Obonyo; C Newbold; S Gupta; K Marsh
Journal:  Lancet       Date:  1997-06-07       Impact factor: 79.321

6.  The role of low level Plasmodium falciparum parasitaemia in anaemia among infants living in an area of intense and perennial transmission.

Authors:  A Y Kitua; T A Smith; P L Alonso; H Urassa; H Masanja; J Kimario; M Tanner
Journal:  Trop Med Int Health       Date:  1997-04       Impact factor: 2.622

7.  Association of transmission intensity and age with clinical manifestations and case fatality of severe Plasmodium falciparum malaria.

Authors:  Hugh Reyburn; Redempta Mbatia; Chris Drakeley; Jane Bruce; Ilona Carneiro; Raimos Olomi; Jonathan Cox; W M M M Nkya; Martha Lemnge; Brian M Greenwood; Eleanor M Riley
Journal:  JAMA       Date:  2005-03-23       Impact factor: 56.272

Review 8.  Conquering the intolerable burden of malaria: what's new, what's needed: a summary.

Authors:  Joel G Breman; Martin S Alilio; Anne Mills
Journal:  Am J Trop Med Hyg       Date:  2004-08       Impact factor: 2.345

Review 9.  The consequences of reducing transmission of Plasmodium falciparum in Africa.

Authors:  Robert W Snow; Kevin Marsh
Journal:  Adv Parasitol       Date:  2002       Impact factor: 3.870

10.  Potential impact of intermittent preventive treatment (IPT) on spread of drug-resistant malaria.

Authors:  Wendy Prudhomme O'Meara; David L Smith; F Ellis McKenzie
Journal:  PLoS Med       Date:  2006-04-04       Impact factor: 11.069
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  2 in total

1.  Mathematical modeling of malaria infection with innate and adaptive immunity in individuals and agent-based communities.

Authors:  David Gurarie; Stephan Karl; Peter A Zimmerman; Charles H King; Timothy G St Pierre; Timothy M E Davis
Journal:  PLoS One       Date:  2012-03-28       Impact factor: 3.240

Review 2.  Agent-based models of malaria transmission: a systematic review.

Authors:  Neal R Smith; James M Trauer; Manoj Gambhir; Jack S Richards; Richard J Maude; Jonathan M Keith; Jennifer A Flegg
Journal:  Malar J       Date:  2018-08-17       Impact factor: 2.979
  2 in total

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