Literature DB >> 17708915

Recent advances on cyclins, CDKs and CDK inhibitors.

C Martin-Castellanos1.   

Abstract

In eukaryotes, cell division is controlled by cyclin-dependent kinases (CDKs). Here we summarize a few new developments on the regulation of the cell cycle by CDK-cyclin complexes. We have focused on three aspects in which there has been recent progress: the structural analysis of these complexes, the phenotypes of mice carrying knockouts of CDK inhibitors and the role of proteolysis in the regulation of the cell cycle.

Entities:  

Year:  1997        PMID： 17708915     DOI： 10.1016/S0962-8924(96)10055-6

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  9 in total

1.  Regulation of a Myb transcription factor by cyclin-dependent kinase 2 in Giardia lamblia.

Authors:  Chao-Cheng Cho; Li-Hsin Su; Yu-Chang Huang; Yu-Jiao Pan; Chin-Hung Sun
Journal:  J Biol Chem       Date:  2011-12-13       Impact factor: 5.157

2.  Inhibition of cyclin E-cyclin-dependent kinase 2 complex formation and activity is associated with cell cycle arrest and withdrawal in oligodendrocyte progenitor cells.

Authors:  C Ghiani; V Gallo
Journal:  J Neurosci       Date:  2001-02-15       Impact factor: 6.167

3.  Opposite transcriptional effects of cyclic AMP-responsive elements in confluent or p27KIP-overexpressing cells versus serum-starved or growing cells.

Authors:  L Deleu; F Fuks; D Spitkovsky; R Hörlein; S Faisst; J Rommelaere
Journal:  Mol Cell Biol       Date:  1998-01       Impact factor: 4.272

4.  Potassium-induced apoptosis in rat cerebellar granule cells involves cell-cycle blockade at the G1/S transition.

Authors:  F J Martín-Romero; B Santiago-Josefat; J Correa-Bordes; C Gutierrez-Merino; P Fernandez-Salguero
Journal:  J Mol Neurosci       Date:  2000-12       Impact factor: 3.444

5.  Cell cycle arrest and reversion of Ras-induced transformation by a conditionally activated form of mitogen-activated protein kinase kinase kinase 3.

Authors:  H Ellinger-Ziegelbauer; K Kelly; U Siebenlist
Journal:  Mol Cell Biol       Date:  1999-05       Impact factor: 4.272

6.  Roscovitine, a specific inhibitor of cellular cyclin-dependent kinases, inhibits herpes simplex virus DNA synthesis in the presence of viral early proteins.

Authors:  L M Schang; A Rosenberg; P A Schaffer
Journal:  J Virol       Date:  2000-03       Impact factor: 5.103

7.  Voltage-activated K+ channels and membrane depolarization regulate accumulation of the cyclin-dependent kinase inhibitors p27(Kip1) and p21(CIP1) in glial progenitor cells.

Authors:  C A Ghiani; X Yuan; A M Eisen; P L Knutson; R A DePinho; C J McBain; V Gallo
Journal:  J Neurosci       Date:  1999-07-01       Impact factor: 6.167

8.  Distinct glucocorticoid receptor transcriptional regulatory surfaces mediate the cytotoxic and cytostatic effects of glucocorticoids.

Authors:  I Rogatsky; A B Hittelman; D Pearce; M J Garabedian
Journal:  Mol Cell Biol       Date:  1999-07       Impact factor: 4.272

9.  The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein.

Authors:  M E Garber; P Wei; V N KewalRamani; T P Mayall; C H Herrmann; A P Rice; D R Littman; K A Jones
Journal:  Genes Dev       Date:  1998-11-15       Impact factor: 11.361
  9 in total

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