AIM: To discuss the safety of donors during living donor liver transplantation (LDLT) and the authors' experience with 50 cases. METHODS: Between January 1995 and March 2006, 50 patients with end-stage liver disease received LDLT in our department. Donors (at the age of 27-58 years) were healthy and antibody (ABO)-compatible. The protocol of evaluation and selection of donors, choice of surgical methods and strategy applied in the safety evaluation of donors were analyzed. RESULTS: A total of 115 candidate donors were evaluated for LDLT at our center. Of these, 50 underwent successful hepatectomy for living donation. The elimination rate for donors was 43.5%. Positive hepatitis serology and ABO incompatibility were the main factors for excluding candidates. All donors recovered uneventfully. The follow-up time ranged from 3 to 135 mo. The incidence of major and minor medical complications was 12.0% and 28.0%, respectively. CONCLUSION: LDLT provides an excellent approach to the problem of donor shortage in China. With a thorough and complete preoperative workup and meticulous intra- and postoperative management, LDLT can be performed with minimal donor morbidity.
AIM: To discuss the safety of donors during living donor liver transplantation (LDLT) and the authors' experience with 50 cases. METHODS: Between January 1995 and March 2006, 50 patients with end-stage liver disease received LDLT in our department. Donors (at the age of 27-58 years) were healthy and antibody (ABO)-compatible. The protocol of evaluation and selection of donors, choice of surgical methods and strategy applied in the safety evaluation of donors were analyzed. RESULTS: A total of 115 candidate donors were evaluated for LDLT at our center. Of these, 50 underwent successful hepatectomy for living donation. The elimination rate for donors was 43.5%. Positive hepatitis serology and ABO incompatibility were the main factors for excluding candidates. All donors recovered uneventfully. The follow-up time ranged from 3 to 135 mo. The incidence of major and minor medical complications was 12.0% and 28.0%, respectively. CONCLUSION: LDLT provides an excellent approach to the problem of donor shortage in China. With a thorough and complete preoperative workup and meticulous intra- and postoperative management, LDLT can be performed with minimal donor morbidity.
Authors: M Manyalich; C Cabrer; R Valero; D Paredes; A Navarro; E Trias; A Vilarrodona; A Ruiz; C Rodriguez; G Paez Journal: Transplant Proc Date: 2003-11 Impact factor: 1.066
Authors: A Marcos; R A Fisher; J M Ham; A T Olzinski; M L Shiffman; A J Sanyal; V A Luketic; R K Sterling; M E Olbrisch; M P Posner Journal: Transplantation Date: 2000-06-15 Impact factor: 4.939
Authors: J C Emond; T G Heffron; E O Kortz; R Gonzalez-Vallina; J C Contis; D D Black; P F Whitington Journal: Transplantation Date: 1993-04 Impact factor: 4.939
Authors: C E Broelsch; P F Whitington; J C Emond; T G Heffron; J R Thistlethwaite; L Stevens; J Piper; S H Whitington; J L Lichtor Journal: Ann Surg Date: 1991-10 Impact factor: 12.969