Literature DB >> 17708532

DNA methylation: the nuts and bolts of repression.

Tina Branscombe Miranda1, Peter A Jones.   

Abstract

DNA methylation is an epigenetic modification which plays an important role in chromatin organization and gene expression. DNA methylation can silence genes and repetitive elements through a process which leads to the alteration of chromatin structure. The mechanisms which target DNA methylation to specific sites in the genome are not fully understood. In this review, we will discuss the mechanisms which lead to the long-term silencing of genes and will survey the progression that has been made in determining the targeted mechanisms for de novo DNA methylation.

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Year:  2007        PMID： 17708532     DOI： 10.1002/jcp.21224

Source DB:  PubMed          Journal:  J Cell Physiol        ISSN： 0021-9541            Impact factor:   6.384


  224 in total

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2.  Detection of β cell death in diabetes using differentially methylated circulating DNA.

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Authors:  Sayyed K Zaidi; Daniel W Young; Martin Montecino; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
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5.  Epigenetic regulation of myofibroblast differentiation by DNA methylation.

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6.  The mutational spectrum of non-CpG DNA varies with CpG content.

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Journal:  Genome Res       Date:  2010-05-24       Impact factor: 9.043

7.  Differentiation of neural-crest-derived intermediate pluripotent progenitors into committed periodontal populations involves unique molecular signature changes, cohort shifts, and epigenetic modifications.

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Journal:  Stem Cells Dev       Date:  2010-09-06       Impact factor: 3.272

Review 8.  BDNF-TrkB signaling and neuroprotection in schizophrenia.

Authors:  Chirayu D Pandya; Ammar Kutiyanawalla; Anilkumar Pillai
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9.  Effect of estrogen receptor α binding on functional DNA methylation in breast cancer.

Authors:  Matthew Ung; Xiaotu Ma; Kevin C Johnson; Brock C Christensen; Chao Cheng
Journal:  Epigenetics       Date:  2014-01-16       Impact factor: 4.528

10.  miR-29b induces SOCS-1 expression by promoter demethylation and negatively regulates migration of multiple myeloma and endothelial cells.

Authors:  Nicola Amodio; Dina Bellizzi; Marzia Leotta; Lavinia Raimondi; Lavinia Biamonte; Patrizia D'Aquila; Maria Teresa Di Martino; Teresa Calimeri; Marco Rossi; Marta Lionetti; Emanuela Leone; Giuseppe Passarino; Antonino Neri; Antonio Giordano; Pierosandro Tagliaferri; Pierfrancesco Tassone
Journal:  Cell Cycle       Date:  2013-09-25       Impact factor: 4.534
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